Abstract
Analytical methods for quantitative enantioselective measurements are highly desirable in the life sciences. Existing technologies have disadvantages such as limited temporal resolution, the need for molecular labeling, or high experimental complexity. To overcome these limitations, this work presents a method based on
conventional Raman spectroscopy. A systematic investigation of the key parameters is carried out. It is demonstrated that their careful choice provides an opportunity for enantioselective and quantitative analysis of enantiopure systems as well as enantiomer mixtures.
conventional Raman spectroscopy. A systematic investigation of the key parameters is carried out. It is demonstrated that their careful choice provides an opportunity for enantioselective and quantitative analysis of enantiopure systems as well as enantiomer mixtures.
Original language | English |
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Pages (from-to) | 5012-5018 |
Number of pages | 7 |
Journal | Analyst |
Volume | 140 |
Issue number | 15 |
Early online date | 4 Jun 2015 |
DOIs | |
Publication status | Published - 7 Aug 2015 |
Bibliographical note
Date of Acceptance: 04/06/2015Keywords
- Raman Spectroscopy