Quantitative enantioselective Raman spectroscopy

Johannes Kiefer

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Analytical methods for quantitative enantioselective measurements are highly desirable in the life sciences. Existing technologies have disadvantages such as limited temporal resolution, the need for molecular labeling, or high experimental complexity. To overcome these limitations, this work presents a method based on
conventional Raman spectroscopy. A systematic investigation of the key parameters is carried out. It is demonstrated that their careful choice provides an opportunity for enantioselective and quantitative analysis of enantiopure systems as well as enantiomer mixtures.
Original languageEnglish
Pages (from-to)5012-5018
Number of pages7
JournalAnalyst
Volume140
Issue number15
Early online date4 Jun 2015
DOIs
Publication statusPublished - 7 Aug 2015

Keywords

  • Raman Spectroscopy

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