TY - JOUR
T1 - Randomised controlled trial comparing the clinical and cost-effectiveness of various washout policies versus no washout policy in preventing catheter associated complications in adults living with long-term catheters: study protocol for the CATHETER II study
AU - Abdel-fattah, Mohamed
AU - Johnson, Diana
AU - Constable, Lynda
AU - Thomas, Ruth
AU - Cotton, Seonaidh
AU - Tripathee, Sheela
AU - Cooper, David
AU - Boran, Sue
AU - Dimitropoulos, Konstantinos
AU - Evans, Suzanne
AU - Granitsiotis, Paraskeve
AU - Hashim, Hashim
AU - Kilonzo, Mary
AU - Larcombe, James
AU - Little, Paul
AU - MacLennan, Sara
AU - Murchie, Peter
AU - Myint, Phyo
AU - N’Dow, James
AU - Norrie, John
AU - Omar, Muhammad Imran
AU - Paterson, Catherine
AU - Scotland, Graham
AU - Thiruchelvam, Nikesh
AU - MacLennan, Graeme
N1 - Acknowledgements
We gratefully acknowledge B. Braun Medical AG for donating the supply of washout solutions for use in the CATHETER II study. We are grateful for the secretarial and data coordination support from Dianne Dejean. The research team acknowledges the support from the NHS Research Scotland Primary Care Network (particularly Amanda Cardy for support in patient recruitment). The authors also gratefully acknowledge the support of the Centre for Healthcare Randomised Trials; the Clinical Research Networks; the site teams, participants and their carers; and the Trial Steering and Data Monitoring Committees. We are also grateful to Hanne Bruhn for her help in drafting some of the patient-facing documentation for the study.
Funding
The study is funded by the National Institute for Health Research (NIHR) Health Technology Assessment Programme (17/30/02). The views expressed are those of the authors and not necessarily those of the NIHR or Department of Health and Social Care.
PY - 2022/8/4
Y1 - 2022/8/4
N2 - Various washout policies are widely used in adults living with long-term catheters (LTC). There is currently insufficient evidence on the benefits and potential harms of prophylactic LTC washout policies in the prevention of blockages and other LTC-related adverse events, such as urinary tract infections. CATHETER II tests the hypothesis that weekly prophylactic LTC washouts (normal saline or citric acid) in addition to standard LTC care reduce the incidence of catheter blockage requiring intervention compared to standard LTC care only in adults living with LTC.
AB - Various washout policies are widely used in adults living with long-term catheters (LTC). There is currently insufficient evidence on the benefits and potential harms of prophylactic LTC washout policies in the prevention of blockages and other LTC-related adverse events, such as urinary tract infections. CATHETER II tests the hypothesis that weekly prophylactic LTC washouts (normal saline or citric acid) in addition to standard LTC care reduce the incidence of catheter blockage requiring intervention compared to standard LTC care only in adults living with LTC.
KW - Catheter blockage
KW - Catheter washout solutions
KW - Catheter maintenance solutions
KW - Indwelling catheter
KW - Long-term catheter
KW - Symptomatic catheter-associated urinary tract infection
U2 - 10.1186/s13063-022-06577-2
DO - 10.1186/s13063-022-06577-2
M3 - Article
C2 - 35927733
VL - 23
JO - Trials
JF - Trials
SN - 1745-6215
IS - 1
M1 - 630
ER -