Randomized trial of aromatherapy. Successful treatment for alopecia areata

Isabelle Hay, M Jamieson, Anthony Ormerod

Research output: Contribution to journalArticle

86 Citations (Scopus)

Abstract

OBJECTIVE: To investigate the efficacy of aromatherapy in the treatment of patients with alopecia areata. DESIGN: A randomized, double-blind, controlled trial of 7 months' duration, with follow-up at 3 and 7 months. SETTING: Dermatology outpatient department. PARTICIPANTS: Eighty-six patients diagnosed as having alopecia areata. INTERVENTION: Eighty-six patients were randomized into 2 groups. The active group massaged essential oils (thyme, rosemary, lavender, and cedarwood) in a mixture of carrier oils (jojoba and grapeseed) into their scalp daily. The control group used only carrier oils for their massage, also daily. MAIN OUTCOME MEASURES: Treatment success was evaluated on sequential photographs by 2 dermatologists (I.C.H. and A.D.O.) independently. Similarly, the degree of improvement was measured by 2 methods: a 6-point scale and computerized analysis of traced areas of alopecia. RESULTS: Nineteen (44%) of 43 patients in the active group showed improvement compared with 6 (15%) of 41 patients in the control group (P = .008). An alopecia scale was applied by blinded observers on sequential photographs and was shown to be reproducible with good interobserver agreement (kappa = 0.84). The degree of improvement on photographic assessment was significant (P = .05). Demographic analysis showed that the 2 groups were well matched for prognostic factors. CONCLUSIONS: The results show aromatherapy to be a safe and effective treatment for alopecia areata. Treatment with these essential oils was significantly more effective than treatment with the carrier oil alone (P = .008 for the primary outcome measure). We also successfully applied an evidence-based method to an alternative therapy.
Original languageEnglish
Pages (from-to)1349-1352
Number of pages4
JournalArchives of Dermatology
Volume134
Issue number11
Publication statusPublished - 1 Nov 1998

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Aromatherapy
Alopecia Areata
Alopecia
Volatile Oils
Oils
Lavandula
Thymus Plant
Therapeutics
Control Groups
Massage
Complementary Therapies
Dermatology
Scalp
Outpatients
Demography
Outcome Assessment (Health Care)

Keywords

  • Adult
  • Alopecia Areata
  • Aromatherapy
  • Double-Blind Method
  • Follow-Up Studies
  • Humans
  • Middle Aged
  • Remission Induction

Cite this

Hay, I., Jamieson, M., & Ormerod, A. (1998). Randomized trial of aromatherapy. Successful treatment for alopecia areata. Archives of Dermatology, 134(11), 1349-1352.

Randomized trial of aromatherapy. Successful treatment for alopecia areata. / Hay, Isabelle; Jamieson, M; Ormerod, Anthony.

In: Archives of Dermatology, Vol. 134, No. 11, 01.11.1998, p. 1349-1352.

Research output: Contribution to journalArticle

Hay, I, Jamieson, M & Ormerod, A 1998, 'Randomized trial of aromatherapy. Successful treatment for alopecia areata', Archives of Dermatology, vol. 134, no. 11, pp. 1349-1352.
Hay, Isabelle ; Jamieson, M ; Ormerod, Anthony. / Randomized trial of aromatherapy. Successful treatment for alopecia areata. In: Archives of Dermatology. 1998 ; Vol. 134, No. 11. pp. 1349-1352.
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AB - OBJECTIVE: To investigate the efficacy of aromatherapy in the treatment of patients with alopecia areata. DESIGN: A randomized, double-blind, controlled trial of 7 months' duration, with follow-up at 3 and 7 months. SETTING: Dermatology outpatient department. PARTICIPANTS: Eighty-six patients diagnosed as having alopecia areata. INTERVENTION: Eighty-six patients were randomized into 2 groups. The active group massaged essential oils (thyme, rosemary, lavender, and cedarwood) in a mixture of carrier oils (jojoba and grapeseed) into their scalp daily. The control group used only carrier oils for their massage, also daily. MAIN OUTCOME MEASURES: Treatment success was evaluated on sequential photographs by 2 dermatologists (I.C.H. and A.D.O.) independently. Similarly, the degree of improvement was measured by 2 methods: a 6-point scale and computerized analysis of traced areas of alopecia. RESULTS: Nineteen (44%) of 43 patients in the active group showed improvement compared with 6 (15%) of 41 patients in the control group (P = .008). An alopecia scale was applied by blinded observers on sequential photographs and was shown to be reproducible with good interobserver agreement (kappa = 0.84). The degree of improvement on photographic assessment was significant (P = .05). Demographic analysis showed that the 2 groups were well matched for prognostic factors. CONCLUSIONS: The results show aromatherapy to be a safe and effective treatment for alopecia areata. Treatment with these essential oils was significantly more effective than treatment with the carrier oil alone (P = .008 for the primary outcome measure). We also successfully applied an evidence-based method to an alternative therapy.

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