Recent advances in continuous crystallization

Aniruddha Majumder* (Corresponding Author), Zoltan K. Nagy, Xiong-Wei Ni

*Corresponding author for this work

Research output: Contribution to journalEditorialpeer-review

1 Citation (Scopus)

Abstract

Crystallization is an important means for separation, purification, and manufacturing of pharmaceutical and fine chemical products. Continuous crystallization has attracted significant attention in recent years due to the efforts put in by the pharmaceutical industry and researchers around the globe with encouragement from the leading pharmaceutical regulatory authorities in order to transition from batch to continuous manufacturing. The continuous manufacturing is characterized by a more efficient, flexible, easily scalable, more reliable process compared to its batch counterpart. The recent COVID-19 global pandemic has also underscored the importance of achieving the capability to ramp up pharmaceutical production in short notice while following the stringent regulations to mitigate the potential shortage of lifesaving drugs. Therefore, the pharmaceutical industry is aspiring to achieve a plant-wide continuous manufacturing for which continuous crystallization plays a critical role as one of the main unit operations...
Original languageEnglish
Pages (from-to)610-613
Number of pages4
JournalChemical Engineering Research & Design
Volume186
Early online date1 Sept 2022
DOIs
Publication statusPublished - 1 Oct 2022

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