Recent Asian origin of chytrid fungi causing global amphibian declines

Simon J O'Hanlon (Corresponding Author), Adrien Rieux, Rhys A Farrer, Gonçalo M Rosa, Bruce Waldman, Arnaud Bataille, Tiffany A Kosch, Kris A Murray, Balázs Brankovics, Matteo Fumagalli, Michael D Martin, Nathan Wales, Mario Alvarado-Rybak, Kieran A Bates, Lee Berger, Susanne Böll, Lola Brookes, Frances Clare, Elodie A Courtois, Andrew A CunninghamThomas M Doherty-Bone, Pria Ghosh, David J Gower, William E Hintz, Jacob Höglund, Thomas S Jenkinson, Chun-Fu Lin, Anssi Laurila, Adeline Loyau, An Martel, Sara Meurling, Claude Miaud, Pete Minting, Frank Pasmans, Dirk S Schmeller, Benedikt R Schmidt, Jennifer M G Shelton, Lee F Skerratt, Freya Smith, Claudio Soto-Azat, Matteo Spagnoletti, Giulia Tessa, Luís Felipe Toledo, Andrés Valenzuela-Sánchez, Ruhan Verster, Judit Vörös, Rebecca J Webb, Claudia Wierzbicki, Emma Wombwell, Kelly R Zamudio, David M Aanensen, Timothy Y James, M Thomas P Gilbert, Ché Weldon, Jaime Bosch, François Balloux, Trenton W J Garner, Matthew C Fisher

Research output: Contribution to journalArticle

108 Citations (Scopus)

Abstract

Globalized infectious diseases are causing species declines worldwide, but their source often remains elusive. We used whole-genome sequencing to solve the spatiotemporal origins of the most devastating panzootic to date, caused by the fungus Batrachochytrium dendrobatidis, a proximate driver of global amphibian declines. We traced the source of B. dendrobatidis to the Korean peninsula, where one lineage, BdASIA-1, exhibits the genetic hallmarks of an ancestral population that seeded the panzootic. We date the emergence of this pathogen to the early 20th century, coinciding with the global expansion of commercial trade in amphibians, and we show that intercontinental transmission is ongoing. Our findings point to East Asia as a geographic hotspot for B. dendrobatidis biodiversity and the original source of these lineages that now parasitize amphibians worldwide.

Original languageEnglish
Pages (from-to)621-627
Number of pages7
JournalScience
Volume360
Issue number6389
DOIs
Publication statusPublished - 11 May 2018

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Keywords

  • Africa
  • Americas
  • Amphibians/microbiology
  • Animals
  • Asia
  • Australia
  • Chytridiomycota/classification
  • Europe
  • Extinction, Biological
  • Genes, Fungal
  • Genetic Variation
  • Hybridization, Genetic
  • Korea
  • Phylogeny
  • Sequence Analysis, DNA
  • Virulence

Cite this

O'Hanlon, S. J., Rieux, A., Farrer, R. A., Rosa, G. M., Waldman, B., Bataille, A., Kosch, T. A., Murray, K. A., Brankovics, B., Fumagalli, M., Martin, M. D., Wales, N., Alvarado-Rybak, M., Bates, K. A., Berger, L., Böll, S., Brookes, L., Clare, F., Courtois, E. A., ... Fisher, M. C. (2018). Recent Asian origin of chytrid fungi causing global amphibian declines. Science, 360(6389), 621-627. https://doi.org/10.1126/science.aar1965