Reconstitution of UCP1 using CRISPR/Cas9 in the white adipose tissue of pigs decreases fat deposition and improves thermogenic capacity

Qiantao Zheng, Jun Lin, Jiaojiao Huang, Hongyong Zhang, Rui Zhang, Xueying Zhang, Chunwei Cao, Catherine Hambly, Guosong Qin, Jing Yao, Ruigao Song, Qitao Jia, Xiao Wang, Yongshun Li, Nan Zhang, Zhengyu Piao, Rongcai Ye, John R Speakman, Hongmei Wang, Qi ZhouYanfang Wang* (Corresponding Author), Wanzhu Jin* (Corresponding Author), Jianguo Zhao* (Corresponding Author)

*Corresponding author for this work

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Medicine & Life Sciences