Reduction in colposcopy workload and associated clinical activity following HPV catch-up vaccination programme in Scotland: an ecological study

M. E. Cruickshank, J. Pan, S. C. Cotton, K. Kavanagh, C. Robertson, K. Cuschieri, H. Cubie, T. Palmer, K. G. Pollock

Research output: Contribution to journalArticle

6 Citations (Scopus)
6 Downloads (Pure)

Abstract

ObjectiveTo measure patterns of clinical activity at colposcopy before and after vaccinated women entered the Scottish Cervical Screening Programme (SCSP).DesignPopulation-based observational study using nationally collected data.SettingScottish colposcopy clinicsSampleAll women with a date of birth on or after 1 January 1985 who attended colposcopy in Scotland between 2008 and 2014.MethodsRoutinely collected data from the Scottish National Colposcopy Clinical Information Audit System (NCCIAS) were extracted, including: referral criteria, referral cervical cytology, colposcopic findings, clinical procedures, and histology results. Analysis was restricted to those referred to colposcopy at age 20 or 21 years.Main outcome measuresReferral criteria, positive predictive value of colposcopy, default rates, and rates of cervical biopsies and treatments.ResultsA total of 7372 women referred for colposcopy at age 20 or 21 years were identified. There was a downward trend in the proportion of those referred with abnormal cytology (2008/9, 91.0%; 2013/14, 90.3%; linear trend P = 0.03). Women were less likely to have diagnostic or therapeutic interventions. The proportion with no biopsy (2008/9, 19.5%; 2013/14, 26.9%; linear trend P < 0.0001) and no treatment (2008/9, 74.9%; 2013/14, 91.8%; linear trend P < 0.0001) increased over the period of observation.ConclusionsA reduction in clinical activity related to abnormal screening referrals is likely to be associated with the human papillomavirus (HPV) catch-up immunisation programme. Referral criteria and the service provision of colposcopy needs to be planned carefully, taking account of the increasing number of women who have been immunised against HPV that will be entering cervical screening programmes worldwide.
Original languageEnglish
Pages (from-to)1386-1393
Number of pages8
JournalBJOG-An International Journal of Obstetrics and Gynaecology
Volume124
Issue number9
Early online date9 Mar 2017
DOIs
Publication statusPublished - Aug 2017

Fingerprint

Colposcopy
Scotland
Workload
Human Activities
Vaccination
Referral and Consultation
Cell Biology
Clinical Audit
Biopsy
Immunization Programs
Information Systems
Observational Studies
Histology
Therapeutics
Observation
Parturition

Keywords

  • HPV
  • HPV vaccine
  • immunisation
  • cervical screening
  • colposcopy
  • loop excision

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Reduction in colposcopy workload and associated clinical activity following HPV catch-up vaccination programme in Scotland : an ecological study. / Cruickshank, M. E.; Pan, J.; Cotton, S. C.; Kavanagh, K.; Robertson, C.; Cuschieri, K.; Cubie, H.; Palmer, T.; Pollock, K. G.

In: BJOG-An International Journal of Obstetrics and Gynaecology, Vol. 124, No. 9, 08.2017, p. 1386-1393.

Research output: Contribution to journalArticle

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title = "Reduction in colposcopy workload and associated clinical activity following HPV catch-up vaccination programme in Scotland: an ecological study",
abstract = "ObjectiveTo measure patterns of clinical activity at colposcopy before and after vaccinated women entered the Scottish Cervical Screening Programme (SCSP).DesignPopulation-based observational study using nationally collected data.SettingScottish colposcopy clinicsSampleAll women with a date of birth on or after 1 January 1985 who attended colposcopy in Scotland between 2008 and 2014.MethodsRoutinely collected data from the Scottish National Colposcopy Clinical Information Audit System (NCCIAS) were extracted, including: referral criteria, referral cervical cytology, colposcopic findings, clinical procedures, and histology results. Analysis was restricted to those referred to colposcopy at age 20 or 21 years.Main outcome measuresReferral criteria, positive predictive value of colposcopy, default rates, and rates of cervical biopsies and treatments.ResultsA total of 7372 women referred for colposcopy at age 20 or 21 years were identified. There was a downward trend in the proportion of those referred with abnormal cytology (2008/9, 91.0{\%}; 2013/14, 90.3{\%}; linear trend P = 0.03). Women were less likely to have diagnostic or therapeutic interventions. The proportion with no biopsy (2008/9, 19.5{\%}; 2013/14, 26.9{\%}; linear trend P < 0.0001) and no treatment (2008/9, 74.9{\%}; 2013/14, 91.8{\%}; linear trend P < 0.0001) increased over the period of observation.ConclusionsA reduction in clinical activity related to abnormal screening referrals is likely to be associated with the human papillomavirus (HPV) catch-up immunisation programme. Referral criteria and the service provision of colposcopy needs to be planned carefully, taking account of the increasing number of women who have been immunised against HPV that will be entering cervical screening programmes worldwide.",
keywords = "HPV, HPV vaccine, immunisation, cervical screening, colposcopy, loop excision",
author = "Cruickshank, {M. E.} and J. Pan and Cotton, {S. C.} and K. Kavanagh and C. Robertson and K. Cuschieri and H. Cubie and T. Palmer and Pollock, {K. G.}",
note = "Funding This study was funded by a Chief Scientist Office Programme grant (CSO reference number CZH/4/528).",
year = "2017",
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TY - JOUR

T1 - Reduction in colposcopy workload and associated clinical activity following HPV catch-up vaccination programme in Scotland

T2 - an ecological study

AU - Cruickshank, M. E.

AU - Pan, J.

AU - Cotton, S. C.

AU - Kavanagh, K.

AU - Robertson, C.

AU - Cuschieri, K.

AU - Cubie, H.

AU - Palmer, T.

AU - Pollock, K. G.

N1 - Funding This study was funded by a Chief Scientist Office Programme grant (CSO reference number CZH/4/528).

PY - 2017/8

Y1 - 2017/8

N2 - ObjectiveTo measure patterns of clinical activity at colposcopy before and after vaccinated women entered the Scottish Cervical Screening Programme (SCSP).DesignPopulation-based observational study using nationally collected data.SettingScottish colposcopy clinicsSampleAll women with a date of birth on or after 1 January 1985 who attended colposcopy in Scotland between 2008 and 2014.MethodsRoutinely collected data from the Scottish National Colposcopy Clinical Information Audit System (NCCIAS) were extracted, including: referral criteria, referral cervical cytology, colposcopic findings, clinical procedures, and histology results. Analysis was restricted to those referred to colposcopy at age 20 or 21 years.Main outcome measuresReferral criteria, positive predictive value of colposcopy, default rates, and rates of cervical biopsies and treatments.ResultsA total of 7372 women referred for colposcopy at age 20 or 21 years were identified. There was a downward trend in the proportion of those referred with abnormal cytology (2008/9, 91.0%; 2013/14, 90.3%; linear trend P = 0.03). Women were less likely to have diagnostic or therapeutic interventions. The proportion with no biopsy (2008/9, 19.5%; 2013/14, 26.9%; linear trend P < 0.0001) and no treatment (2008/9, 74.9%; 2013/14, 91.8%; linear trend P < 0.0001) increased over the period of observation.ConclusionsA reduction in clinical activity related to abnormal screening referrals is likely to be associated with the human papillomavirus (HPV) catch-up immunisation programme. Referral criteria and the service provision of colposcopy needs to be planned carefully, taking account of the increasing number of women who have been immunised against HPV that will be entering cervical screening programmes worldwide.

AB - ObjectiveTo measure patterns of clinical activity at colposcopy before and after vaccinated women entered the Scottish Cervical Screening Programme (SCSP).DesignPopulation-based observational study using nationally collected data.SettingScottish colposcopy clinicsSampleAll women with a date of birth on or after 1 January 1985 who attended colposcopy in Scotland between 2008 and 2014.MethodsRoutinely collected data from the Scottish National Colposcopy Clinical Information Audit System (NCCIAS) were extracted, including: referral criteria, referral cervical cytology, colposcopic findings, clinical procedures, and histology results. Analysis was restricted to those referred to colposcopy at age 20 or 21 years.Main outcome measuresReferral criteria, positive predictive value of colposcopy, default rates, and rates of cervical biopsies and treatments.ResultsA total of 7372 women referred for colposcopy at age 20 or 21 years were identified. There was a downward trend in the proportion of those referred with abnormal cytology (2008/9, 91.0%; 2013/14, 90.3%; linear trend P = 0.03). Women were less likely to have diagnostic or therapeutic interventions. The proportion with no biopsy (2008/9, 19.5%; 2013/14, 26.9%; linear trend P < 0.0001) and no treatment (2008/9, 74.9%; 2013/14, 91.8%; linear trend P < 0.0001) increased over the period of observation.ConclusionsA reduction in clinical activity related to abnormal screening referrals is likely to be associated with the human papillomavirus (HPV) catch-up immunisation programme. Referral criteria and the service provision of colposcopy needs to be planned carefully, taking account of the increasing number of women who have been immunised against HPV that will be entering cervical screening programmes worldwide.

KW - HPV

KW - HPV vaccine

KW - immunisation

KW - cervical screening

KW - colposcopy

KW - loop excision

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DO - 10.1111/1471-0528.14562

M3 - Article

VL - 124

SP - 1386

EP - 1393

JO - BJOG-An International Journal of Obstetrics and Gynaecology

JF - BJOG-An International Journal of Obstetrics and Gynaecology

SN - 1470-0328

IS - 9

ER -