Regulatory networks controlling Candida albicans morphogenesis

Research output: Contribution to journalLiterature review

246 Citations (Scopus)

Abstract

Candida albicans undergoes reversible morphogenetic transitions between budding, pseudohyphal and hyphal growth forms that promote the virulence of this pathogenic fungus. The regulatory networks that control morphogenesis are being elucidated; however, the primary signals that trigger morphogenesis remain obscure, and the physiological outputs of these networks are complex.

Original languageEnglish
Pages (from-to)333-338
Number of pages6
JournalTrends in Microbiology
Volume7
Publication statusPublished - 1999

Keywords

  • YEAST SACCHAROMYCES-CEREVISIAE
  • PROTEIN ALPHA-SUBUNIT
  • GERM TUBE FORMATION
  • CELL-CYCLE
  • HYPHAL FORMATION
  • BUDDING YEAST
  • GENE FAMILY
  • ASPARTYL PROTEINASES
  • PSEUDOHYPHAL GROWTH
  • SIGNAL-TRANSDUCTION

Cite this

Regulatory networks controlling Candida albicans morphogenesis. / Brown, A J P ; Gow, N A R .

In: Trends in Microbiology, Vol. 7, 1999, p. 333-338.

Research output: Contribution to journalLiterature review

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abstract = "Candida albicans undergoes reversible morphogenetic transitions between budding, pseudohyphal and hyphal growth forms that promote the virulence of this pathogenic fungus. The regulatory networks that control morphogenesis are being elucidated; however, the primary signals that trigger morphogenesis remain obscure, and the physiological outputs of these networks are complex.",
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AU - Brown, A J P

AU - Gow, N A R

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AB - Candida albicans undergoes reversible morphogenetic transitions between budding, pseudohyphal and hyphal growth forms that promote the virulence of this pathogenic fungus. The regulatory networks that control morphogenesis are being elucidated; however, the primary signals that trigger morphogenesis remain obscure, and the physiological outputs of these networks are complex.

KW - YEAST SACCHAROMYCES-CEREVISIAE

KW - PROTEIN ALPHA-SUBUNIT

KW - GERM TUBE FORMATION

KW - CELL-CYCLE

KW - HYPHAL FORMATION

KW - BUDDING YEAST

KW - GENE FAMILY

KW - ASPARTYL PROTEINASES

KW - PSEUDOHYPHAL GROWTH

KW - SIGNAL-TRANSDUCTION

M3 - Literature review

VL - 7

SP - 333

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JO - Trends in Microbiology

JF - Trends in Microbiology

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