Regulatory networks controlling Candida albicans morphogenesis

A J P Brown, N A R Gow

Research output: Contribution to journalLiterature review

251 Citations (Scopus)

Abstract

Candida albicans undergoes reversible morphogenetic transitions between budding, pseudohyphal and hyphal growth forms that promote the virulence of this pathogenic fungus. The regulatory networks that control morphogenesis are being elucidated; however, the primary signals that trigger morphogenesis remain obscure, and the physiological outputs of these networks are complex.

Original languageEnglish
Pages (from-to)333-338
Number of pages6
JournalTrends in Microbiology
Volume7
Publication statusPublished - 1999

Keywords

  • YEAST SACCHAROMYCES-CEREVISIAE
  • PROTEIN ALPHA-SUBUNIT
  • GERM TUBE FORMATION
  • CELL-CYCLE
  • HYPHAL FORMATION
  • BUDDING YEAST
  • GENE FAMILY
  • ASPARTYL PROTEINASES
  • PSEUDOHYPHAL GROWTH
  • SIGNAL-TRANSDUCTION

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