Relation between self-reported physical functional health and chronic disease mortality in men and women in the European Prospective Investigation into Cancer (EPIC-Norfolk): a prospective population study

Phyo K Myint; Robert N Luben; Paul G Surtees; Nicholas W J Wainwright; Ailsa A Welch; Sheila A Bingham; Nicholas E Day; Nicholas J Wareham; Kay-Tee Khaw

doi:10.1016/j.annepidem.2005.04.005

Relation between self-reported physical functional health and chronic disease mortality in men and women in the European Prospective Investigation into Cancer (EPIC-Norfolk): a prospective population study

Phyo K Myint, Robert N Luben, Paul G Surtees, Nicholas W J Wainwright, Ailsa A Welch, Sheila A Bingham, Nicholas E Day, Nicholas J Wareham, Kay-Tee Khaw

Research output: Contribution to journal › Article › peer-review

64 Citations (Scopus)

Abstract

PURPOSE: To explore the relationship between self-reported physical functional health and mortality.

METHODS: A cohort of 17,777 men and women aged 41-80 years who completed the anglicised 36-item short-form questionnaire (UK SF-36) in 1996-2000 were followed prospectively until 2004, average 6.5 years, for mortality from all causes, from cardiovascular disease, from cancer, and from all other causes.

RESULTS: During 115,527 person-years of follow-up, 1065 deaths occurred. After adjusting for age, body mass index, systolic blood pressure, cholesterol, smoking, diabetes, and social class, the relative risks (RR) for all cause mortality were 2.15 (95% CI: 1.54, 2.99) and 2.42 (1.57, 3.74), cardiovascular mortality were RR = 2.71 (1.47, 4.98) and 3.09 (1.30, 7.33), and death from other causes excluding cancer RR = 2.88 (1.43, 5.79) and 5.22 (1.21, 22.53) in men and women respectively for those who were in the lowest compared to top quintile of SF-36 scores. These associations remained unchanged after exclusion of deaths during the first two years of follow-up and were also consistent in different age groups.

CONCLUSIONS: Poor self-reported physical functional health in men and women without known instances of prevalent cardiovascular disease or cancer predicts total and cardiovascular disease mortality in the general population independently of known risk factors.

Original language	English
Pages (from-to)	492-500
Number of pages	9
Journal	Annals of Epidemiology
Volume	16
Issue number	6
DOIs	https://doi.org/10.1016/j.annepidem.2005.04.005
Publication status	Published - Jun 2006

Keywords

Adult
Aged
Aged, 80 and over
Cardiovascular Diseases
Chronic Disease
Cohort Studies
Female
Great Britain
Humans
Male
Middle Aged
Neoplasms
Physical Fitness
Prospective Studies
Self Concept

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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Myint, P. K., Luben, R. N., Surtees, P. G., Wainwright, N. W. J., Welch, A. A., Bingham, S. A., Day, N. E., Wareham, N. J., & Khaw, K.-T. (2006). Relation between self-reported physical functional health and chronic disease mortality in men and women in the European Prospective Investigation into Cancer (EPIC-Norfolk): a prospective population study. Annals of Epidemiology, 16(6), 492-500. https://doi.org/10.1016/j.annepidem.2005.04.005

Relation between self-reported physical functional health and chronic disease mortality in men and women in the European Prospective Investigation into Cancer (EPIC-Norfolk): a prospective population study. / Myint, Phyo K; Luben, Robert N; Surtees, Paul G et al.
In: Annals of Epidemiology, Vol. 16, No. 6, 06.2006, p. 492-500.

Research output: Contribution to journal › Article › peer-review

Myint, PK, Luben, RN, Surtees, PG, Wainwright, NWJ, Welch, AA, Bingham, SA, Day, NE, Wareham, NJ & Khaw, K-T 2006, 'Relation between self-reported physical functional health and chronic disease mortality in men and women in the European Prospective Investigation into Cancer (EPIC-Norfolk): a prospective population study', Annals of Epidemiology, vol. 16, no. 6, pp. 492-500. https://doi.org/10.1016/j.annepidem.2005.04.005

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title = "Relation between self-reported physical functional health and chronic disease mortality in men and women in the European Prospective Investigation into Cancer (EPIC-Norfolk): a prospective population study",

abstract = "PURPOSE: To explore the relationship between self-reported physical functional health and mortality.METHODS: A cohort of 17,777 men and women aged 41-80 years who completed the anglicised 36-item short-form questionnaire (UK SF-36) in 1996-2000 were followed prospectively until 2004, average 6.5 years, for mortality from all causes, from cardiovascular disease, from cancer, and from all other causes.RESULTS: During 115,527 person-years of follow-up, 1065 deaths occurred. After adjusting for age, body mass index, systolic blood pressure, cholesterol, smoking, diabetes, and social class, the relative risks (RR) for all cause mortality were 2.15 (95% CI: 1.54, 2.99) and 2.42 (1.57, 3.74), cardiovascular mortality were RR = 2.71 (1.47, 4.98) and 3.09 (1.30, 7.33), and death from other causes excluding cancer RR = 2.88 (1.43, 5.79) and 5.22 (1.21, 22.53) in men and women respectively for those who were in the lowest compared to top quintile of SF-36 scores. These associations remained unchanged after exclusion of deaths during the first two years of follow-up and were also consistent in different age groups.CONCLUSIONS: Poor self-reported physical functional health in men and women without known instances of prevalent cardiovascular disease or cancer predicts total and cardiovascular disease mortality in the general population independently of known risk factors.",

keywords = "Adult, Aged, Aged, 80 and over, Cardiovascular Diseases, Chronic Disease, Cohort Studies, Female, Great Britain, Humans, Male, Middle Aged, Neoplasms, Physical Fitness, Prospective Studies, Self Concept",

author = "Myint, {Phyo K} and Luben, {Robert N} and Surtees, {Paul G} and Wainwright, {Nicholas W J} and Welch, {Ailsa A} and Bingham, {Sheila A} and Day, {Nicholas E} and Wareham, {Nicholas J} and Kay-Tee Khaw",

year = "2006",

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doi = "10.1016/j.annepidem.2005.04.005",

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T1 - Relation between self-reported physical functional health and chronic disease mortality in men and women in the European Prospective Investigation into Cancer (EPIC-Norfolk)

T2 - a prospective population study

AU - Myint, Phyo K

AU - Luben, Robert N

AU - Surtees, Paul G

AU - Wainwright, Nicholas W J

AU - Welch, Ailsa A

AU - Bingham, Sheila A

AU - Day, Nicholas E

AU - Wareham, Nicholas J

AU - Khaw, Kay-Tee

PY - 2006/6

Y1 - 2006/6

N2 - PURPOSE: To explore the relationship between self-reported physical functional health and mortality.METHODS: A cohort of 17,777 men and women aged 41-80 years who completed the anglicised 36-item short-form questionnaire (UK SF-36) in 1996-2000 were followed prospectively until 2004, average 6.5 years, for mortality from all causes, from cardiovascular disease, from cancer, and from all other causes.RESULTS: During 115,527 person-years of follow-up, 1065 deaths occurred. After adjusting for age, body mass index, systolic blood pressure, cholesterol, smoking, diabetes, and social class, the relative risks (RR) for all cause mortality were 2.15 (95% CI: 1.54, 2.99) and 2.42 (1.57, 3.74), cardiovascular mortality were RR = 2.71 (1.47, 4.98) and 3.09 (1.30, 7.33), and death from other causes excluding cancer RR = 2.88 (1.43, 5.79) and 5.22 (1.21, 22.53) in men and women respectively for those who were in the lowest compared to top quintile of SF-36 scores. These associations remained unchanged after exclusion of deaths during the first two years of follow-up and were also consistent in different age groups.CONCLUSIONS: Poor self-reported physical functional health in men and women without known instances of prevalent cardiovascular disease or cancer predicts total and cardiovascular disease mortality in the general population independently of known risk factors.

AB - PURPOSE: To explore the relationship between self-reported physical functional health and mortality.METHODS: A cohort of 17,777 men and women aged 41-80 years who completed the anglicised 36-item short-form questionnaire (UK SF-36) in 1996-2000 were followed prospectively until 2004, average 6.5 years, for mortality from all causes, from cardiovascular disease, from cancer, and from all other causes.RESULTS: During 115,527 person-years of follow-up, 1065 deaths occurred. After adjusting for age, body mass index, systolic blood pressure, cholesterol, smoking, diabetes, and social class, the relative risks (RR) for all cause mortality were 2.15 (95% CI: 1.54, 2.99) and 2.42 (1.57, 3.74), cardiovascular mortality were RR = 2.71 (1.47, 4.98) and 3.09 (1.30, 7.33), and death from other causes excluding cancer RR = 2.88 (1.43, 5.79) and 5.22 (1.21, 22.53) in men and women respectively for those who were in the lowest compared to top quintile of SF-36 scores. These associations remained unchanged after exclusion of deaths during the first two years of follow-up and were also consistent in different age groups.CONCLUSIONS: Poor self-reported physical functional health in men and women without known instances of prevalent cardiovascular disease or cancer predicts total and cardiovascular disease mortality in the general population independently of known risk factors.

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Cardiovascular Diseases

KW - Chronic Disease

KW - Cohort Studies

KW - Female

KW - Great Britain

KW - Humans

KW - Male

KW - Middle Aged

KW - Neoplasms

KW - Physical Fitness

KW - Prospective Studies

KW - Self Concept

U2 - 10.1016/j.annepidem.2005.04.005

DO - 10.1016/j.annepidem.2005.04.005

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C2 - 16005244

SN - 1047-2797

VL - 16

SP - 492

EP - 500

JO - Annals of Epidemiology

JF - Annals of Epidemiology

IS - 6

ER -