Relation between self-reported physical functional health and chronic disease mortality in men and women in the European Prospective Investigation into Cancer (EPIC-Norfolk): a prospective population study

Phyo K Myint, Robert N Luben, Paul G Surtees, Nicholas W J Wainwright, Ailsa A Welch, Sheila A Bingham, Nicholas E Day, Nicholas J Wareham, Kay-Tee Khaw

Research output: Contribution to journalArticle

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Abstract

PURPOSE: To explore the relationship between self-reported physical functional health and mortality.

METHODS: A cohort of 17,777 men and women aged 41-80 years who completed the anglicised 36-item short-form questionnaire (UK SF-36) in 1996-2000 were followed prospectively until 2004, average 6.5 years, for mortality from all causes, from cardiovascular disease, from cancer, and from all other causes.

RESULTS: During 115,527 person-years of follow-up, 1065 deaths occurred. After adjusting for age, body mass index, systolic blood pressure, cholesterol, smoking, diabetes, and social class, the relative risks (RR) for all cause mortality were 2.15 (95% CI: 1.54, 2.99) and 2.42 (1.57, 3.74), cardiovascular mortality were RR = 2.71 (1.47, 4.98) and 3.09 (1.30, 7.33), and death from other causes excluding cancer RR = 2.88 (1.43, 5.79) and 5.22 (1.21, 22.53) in men and women respectively for those who were in the lowest compared to top quintile of SF-36 scores. These associations remained unchanged after exclusion of deaths during the first two years of follow-up and were also consistent in different age groups.

CONCLUSIONS: Poor self-reported physical functional health in men and women without known instances of prevalent cardiovascular disease or cancer predicts total and cardiovascular disease mortality in the general population independently of known risk factors.

Original languageEnglish
Pages (from-to)492-500
Number of pages9
JournalAnnals of Epidemiology
Volume16
Issue number6
DOIs
Publication statusPublished - Jun 2006

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Chronic Disease
Prospective Studies
Mortality
Health
Cardiovascular Diseases
Population
Neoplasms
Blood Pressure
Men's Health
Women's Health
Social Class
Cause of Death
Body Mass Index
Age Groups
Smoking
Cholesterol

Keywords

  • Adult
  • Aged
  • Aged, 80 and over
  • Cardiovascular Diseases
  • Chronic Disease
  • Cohort Studies
  • Female
  • Great Britain
  • Humans
  • Male
  • Middle Aged
  • Neoplasms
  • Physical Fitness
  • Prospective Studies
  • Self Concept

Cite this

Relation between self-reported physical functional health and chronic disease mortality in men and women in the European Prospective Investigation into Cancer (EPIC-Norfolk) : a prospective population study. / Myint, Phyo K; Luben, Robert N; Surtees, Paul G; Wainwright, Nicholas W J; Welch, Ailsa A; Bingham, Sheila A; Day, Nicholas E; Wareham, Nicholas J; Khaw, Kay-Tee.

In: Annals of Epidemiology, Vol. 16, No. 6, 06.2006, p. 492-500.

Research output: Contribution to journalArticle

Myint, Phyo K ; Luben, Robert N ; Surtees, Paul G ; Wainwright, Nicholas W J ; Welch, Ailsa A ; Bingham, Sheila A ; Day, Nicholas E ; Wareham, Nicholas J ; Khaw, Kay-Tee. / Relation between self-reported physical functional health and chronic disease mortality in men and women in the European Prospective Investigation into Cancer (EPIC-Norfolk) : a prospective population study. In: Annals of Epidemiology. 2006 ; Vol. 16, No. 6. pp. 492-500.
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abstract = "PURPOSE: To explore the relationship between self-reported physical functional health and mortality.METHODS: A cohort of 17,777 men and women aged 41-80 years who completed the anglicised 36-item short-form questionnaire (UK SF-36) in 1996-2000 were followed prospectively until 2004, average 6.5 years, for mortality from all causes, from cardiovascular disease, from cancer, and from all other causes.RESULTS: During 115,527 person-years of follow-up, 1065 deaths occurred. After adjusting for age, body mass index, systolic blood pressure, cholesterol, smoking, diabetes, and social class, the relative risks (RR) for all cause mortality were 2.15 (95{\%} CI: 1.54, 2.99) and 2.42 (1.57, 3.74), cardiovascular mortality were RR = 2.71 (1.47, 4.98) and 3.09 (1.30, 7.33), and death from other causes excluding cancer RR = 2.88 (1.43, 5.79) and 5.22 (1.21, 22.53) in men and women respectively for those who were in the lowest compared to top quintile of SF-36 scores. These associations remained unchanged after exclusion of deaths during the first two years of follow-up and were also consistent in different age groups.CONCLUSIONS: Poor self-reported physical functional health in men and women without known instances of prevalent cardiovascular disease or cancer predicts total and cardiovascular disease mortality in the general population independently of known risk factors.",
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T1 - Relation between self-reported physical functional health and chronic disease mortality in men and women in the European Prospective Investigation into Cancer (EPIC-Norfolk)

T2 - a prospective population study

AU - Myint, Phyo K

AU - Luben, Robert N

AU - Surtees, Paul G

AU - Wainwright, Nicholas W J

AU - Welch, Ailsa A

AU - Bingham, Sheila A

AU - Day, Nicholas E

AU - Wareham, Nicholas J

AU - Khaw, Kay-Tee

PY - 2006/6

Y1 - 2006/6

N2 - PURPOSE: To explore the relationship between self-reported physical functional health and mortality.METHODS: A cohort of 17,777 men and women aged 41-80 years who completed the anglicised 36-item short-form questionnaire (UK SF-36) in 1996-2000 were followed prospectively until 2004, average 6.5 years, for mortality from all causes, from cardiovascular disease, from cancer, and from all other causes.RESULTS: During 115,527 person-years of follow-up, 1065 deaths occurred. After adjusting for age, body mass index, systolic blood pressure, cholesterol, smoking, diabetes, and social class, the relative risks (RR) for all cause mortality were 2.15 (95% CI: 1.54, 2.99) and 2.42 (1.57, 3.74), cardiovascular mortality were RR = 2.71 (1.47, 4.98) and 3.09 (1.30, 7.33), and death from other causes excluding cancer RR = 2.88 (1.43, 5.79) and 5.22 (1.21, 22.53) in men and women respectively for those who were in the lowest compared to top quintile of SF-36 scores. These associations remained unchanged after exclusion of deaths during the first two years of follow-up and were also consistent in different age groups.CONCLUSIONS: Poor self-reported physical functional health in men and women without known instances of prevalent cardiovascular disease or cancer predicts total and cardiovascular disease mortality in the general population independently of known risk factors.

AB - PURPOSE: To explore the relationship between self-reported physical functional health and mortality.METHODS: A cohort of 17,777 men and women aged 41-80 years who completed the anglicised 36-item short-form questionnaire (UK SF-36) in 1996-2000 were followed prospectively until 2004, average 6.5 years, for mortality from all causes, from cardiovascular disease, from cancer, and from all other causes.RESULTS: During 115,527 person-years of follow-up, 1065 deaths occurred. After adjusting for age, body mass index, systolic blood pressure, cholesterol, smoking, diabetes, and social class, the relative risks (RR) for all cause mortality were 2.15 (95% CI: 1.54, 2.99) and 2.42 (1.57, 3.74), cardiovascular mortality were RR = 2.71 (1.47, 4.98) and 3.09 (1.30, 7.33), and death from other causes excluding cancer RR = 2.88 (1.43, 5.79) and 5.22 (1.21, 22.53) in men and women respectively for those who were in the lowest compared to top quintile of SF-36 scores. These associations remained unchanged after exclusion of deaths during the first two years of follow-up and were also consistent in different age groups.CONCLUSIONS: Poor self-reported physical functional health in men and women without known instances of prevalent cardiovascular disease or cancer predicts total and cardiovascular disease mortality in the general population independently of known risk factors.

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Cardiovascular Diseases

KW - Chronic Disease

KW - Cohort Studies

KW - Female

KW - Great Britain

KW - Humans

KW - Male

KW - Middle Aged

KW - Neoplasms

KW - Physical Fitness

KW - Prospective Studies

KW - Self Concept

U2 - 10.1016/j.annepidem.2005.04.005

DO - 10.1016/j.annepidem.2005.04.005

M3 - Article

C2 - 16005244

VL - 16

SP - 492

EP - 500

JO - Annals of Epidemiology

JF - Annals of Epidemiology

SN - 1047-2797

IS - 6

ER -