Relation of adult lifestyle and socioeconomic factors to the prevalence of Helicobacter pylori infection

P. Moayyedi, A. T. R. Axon, R. Feltbower, S. Duffett, W. Crocombe, David Alexander Braunholtz, I. D. G. Richards, A. C. Dowell, D. Forman

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Abstract

Introduction The influence of adult socioeconomic status, co-habitation, gender, smoking, coffee and alcohol intake on risk of Helicobacter pylori infection is uncertain.

Methods Subjects between aged 40-49 years were randomly invited to attend their local primary care centre. Participants were interviewed by a researcher on smoking, coffee and alcohol intake, history of living with a partner, present and childhood socioeconomic conditions. Helicobacter pylori status was determined by C-13-urea breath test.

Results In all, 32 929 subjects were invited, 8429 (26%) were eligible and 2327 (27.6%) were H. pylori positive. Helicobacter pylori infection was more common in men and this association remained after controlling for childhood and adult risk factors in a logistic regression model (odds ratio [OR] = 1.15; 95% CI: 1.03-1.29). Living with a partner was also an independent risk factor for infection (OR = 1.30; 95% CI: 1.01-1.67), particularly in partners of lower social class (social class IV and V-OR = 1.47; 95% CI: 1.19-1.81, compared with social class I and II). Helicobacter pylori infection was more common in lower social class groups (I and II-22% infected, III-29% infected, IV and V-38% infected) and there was a significant increase in risk of infection in manual workers compared with non-manual workers after controlling for other risk factors (OR = 1.18; 95% CI: 1.03-1.34). Alcohol and coffee intake were not independent risk factors for infection and smoking was only a risk factor in those smoking >35 cigarettes a day.

Conclusions Male gender, living with a partner and poor adult socioeconomic conditions are associated with increased risk of H. pylori infection.

Original languageEnglish
Pages (from-to)624-631
Number of pages7
JournalInternational Journal of Epidemiology
Volume31
Issue number3
DOIs
Publication statusPublished - Jun 2002

Keywords

  • Helicobacter pylori
  • gender
  • socioeconomic status
  • LIVING-CONDITIONS
  • TRANSMISSION
  • EPIDEMIOLOGY
  • CHILDHOOD
  • RISK
  • SPOUSES
  • COHORT
  • LIFE

Cite this

Moayyedi, P., Axon, A. T. R., Feltbower, R., Duffett, S., Crocombe, W., Braunholtz, D. A., ... Forman, D. (2002). Relation of adult lifestyle and socioeconomic factors to the prevalence of Helicobacter pylori infection. International Journal of Epidemiology, 31(3), 624-631. https://doi.org/10.1093/ije/31.3.624

Relation of adult lifestyle and socioeconomic factors to the prevalence of Helicobacter pylori infection. / Moayyedi, P.; Axon, A. T. R.; Feltbower, R.; Duffett, S.; Crocombe, W.; Braunholtz, David Alexander; Richards, I. D. G.; Dowell, A. C.; Forman, D.

In: International Journal of Epidemiology, Vol. 31, No. 3, 06.2002, p. 624-631.

Research output: Contribution to journalArticle

Moayyedi, P, Axon, ATR, Feltbower, R, Duffett, S, Crocombe, W, Braunholtz, DA, Richards, IDG, Dowell, AC & Forman, D 2002, 'Relation of adult lifestyle and socioeconomic factors to the prevalence of Helicobacter pylori infection', International Journal of Epidemiology, vol. 31, no. 3, pp. 624-631. https://doi.org/10.1093/ije/31.3.624
Moayyedi, P. ; Axon, A. T. R. ; Feltbower, R. ; Duffett, S. ; Crocombe, W. ; Braunholtz, David Alexander ; Richards, I. D. G. ; Dowell, A. C. ; Forman, D. / Relation of adult lifestyle and socioeconomic factors to the prevalence of Helicobacter pylori infection. In: International Journal of Epidemiology. 2002 ; Vol. 31, No. 3. pp. 624-631.
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abstract = "Introduction The influence of adult socioeconomic status, co-habitation, gender, smoking, coffee and alcohol intake on risk of Helicobacter pylori infection is uncertain.Methods Subjects between aged 40-49 years were randomly invited to attend their local primary care centre. Participants were interviewed by a researcher on smoking, coffee and alcohol intake, history of living with a partner, present and childhood socioeconomic conditions. Helicobacter pylori status was determined by C-13-urea breath test.Results In all, 32 929 subjects were invited, 8429 (26{\%}) were eligible and 2327 (27.6{\%}) were H. pylori positive. Helicobacter pylori infection was more common in men and this association remained after controlling for childhood and adult risk factors in a logistic regression model (odds ratio [OR] = 1.15; 95{\%} CI: 1.03-1.29). Living with a partner was also an independent risk factor for infection (OR = 1.30; 95{\%} CI: 1.01-1.67), particularly in partners of lower social class (social class IV and V-OR = 1.47; 95{\%} CI: 1.19-1.81, compared with social class I and II). Helicobacter pylori infection was more common in lower social class groups (I and II-22{\%} infected, III-29{\%} infected, IV and V-38{\%} infected) and there was a significant increase in risk of infection in manual workers compared with non-manual workers after controlling for other risk factors (OR = 1.18; 95{\%} CI: 1.03-1.34). Alcohol and coffee intake were not independent risk factors for infection and smoking was only a risk factor in those smoking >35 cigarettes a day.Conclusions Male gender, living with a partner and poor adult socioeconomic conditions are associated with increased risk of H. pylori infection.",
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T1 - Relation of adult lifestyle and socioeconomic factors to the prevalence of Helicobacter pylori infection

AU - Moayyedi, P.

AU - Axon, A. T. R.

AU - Feltbower, R.

AU - Duffett, S.

AU - Crocombe, W.

AU - Braunholtz, David Alexander

AU - Richards, I. D. G.

AU - Dowell, A. C.

AU - Forman, D.

PY - 2002/6

Y1 - 2002/6

N2 - Introduction The influence of adult socioeconomic status, co-habitation, gender, smoking, coffee and alcohol intake on risk of Helicobacter pylori infection is uncertain.Methods Subjects between aged 40-49 years were randomly invited to attend their local primary care centre. Participants were interviewed by a researcher on smoking, coffee and alcohol intake, history of living with a partner, present and childhood socioeconomic conditions. Helicobacter pylori status was determined by C-13-urea breath test.Results In all, 32 929 subjects were invited, 8429 (26%) were eligible and 2327 (27.6%) were H. pylori positive. Helicobacter pylori infection was more common in men and this association remained after controlling for childhood and adult risk factors in a logistic regression model (odds ratio [OR] = 1.15; 95% CI: 1.03-1.29). Living with a partner was also an independent risk factor for infection (OR = 1.30; 95% CI: 1.01-1.67), particularly in partners of lower social class (social class IV and V-OR = 1.47; 95% CI: 1.19-1.81, compared with social class I and II). Helicobacter pylori infection was more common in lower social class groups (I and II-22% infected, III-29% infected, IV and V-38% infected) and there was a significant increase in risk of infection in manual workers compared with non-manual workers after controlling for other risk factors (OR = 1.18; 95% CI: 1.03-1.34). Alcohol and coffee intake were not independent risk factors for infection and smoking was only a risk factor in those smoking >35 cigarettes a day.Conclusions Male gender, living with a partner and poor adult socioeconomic conditions are associated with increased risk of H. pylori infection.

AB - Introduction The influence of adult socioeconomic status, co-habitation, gender, smoking, coffee and alcohol intake on risk of Helicobacter pylori infection is uncertain.Methods Subjects between aged 40-49 years were randomly invited to attend their local primary care centre. Participants were interviewed by a researcher on smoking, coffee and alcohol intake, history of living with a partner, present and childhood socioeconomic conditions. Helicobacter pylori status was determined by C-13-urea breath test.Results In all, 32 929 subjects were invited, 8429 (26%) were eligible and 2327 (27.6%) were H. pylori positive. Helicobacter pylori infection was more common in men and this association remained after controlling for childhood and adult risk factors in a logistic regression model (odds ratio [OR] = 1.15; 95% CI: 1.03-1.29). Living with a partner was also an independent risk factor for infection (OR = 1.30; 95% CI: 1.01-1.67), particularly in partners of lower social class (social class IV and V-OR = 1.47; 95% CI: 1.19-1.81, compared with social class I and II). Helicobacter pylori infection was more common in lower social class groups (I and II-22% infected, III-29% infected, IV and V-38% infected) and there was a significant increase in risk of infection in manual workers compared with non-manual workers after controlling for other risk factors (OR = 1.18; 95% CI: 1.03-1.34). Alcohol and coffee intake were not independent risk factors for infection and smoking was only a risk factor in those smoking >35 cigarettes a day.Conclusions Male gender, living with a partner and poor adult socioeconomic conditions are associated with increased risk of H. pylori infection.

KW - Helicobacter pylori

KW - gender

KW - socioeconomic status

KW - LIVING-CONDITIONS

KW - TRANSMISSION

KW - EPIDEMIOLOGY

KW - CHILDHOOD

KW - RISK

KW - SPOUSES

KW - COHORT

KW - LIFE

U2 - 10.1093/ije/31.3.624

DO - 10.1093/ije/31.3.624

M3 - Article

VL - 31

SP - 624

EP - 631

JO - International Journal of Epidemiology

JF - International Journal of Epidemiology

SN - 0300-5771

IS - 3

ER -