Editor—We thank Drs Bailard and Flores for their interesting letter. As they stated, we did not describe intraoperative and postoperative opioid consumption in the study groups, nor did we address the possibility that the apparent survival benefits of receiving non-steroidal anti-inflammatory drugs (NSAIDs) may have resulted in part from their opioid-sparing effect.
Forget, P., & De Koc, M. (2015). Reply from the authors: Direct non-steroidalanti-inflammatory drug effect, rather than an opioid-sparing effect is the most important factor for possibly improved survival after conservative breast surgery. British Journal of Anaesthesia, 114(3), 527-528. https://doi.org/10.1093/bja/aev022