Response to Letter Regarding Article, "the Effect of Selective Heart Rate Slowing in Heart Failure with Preserved Ejection Fraction"

Nikhil Pal, Nadiya Sivaswamy, Masliza Mahmod, Arash Yavari, Amelia Rudd, Satnam Singh, Dana K. Dawson, Jane M. Francis, Jeremy S. Dwight, Hugh Watkins, Stefan Neubauer, Michael Frenneaux, Houman Ashrafian

Research output: Contribution to journalLetter

1 Citation (Scopus)

Abstract

We thank de Dios for their comments related to the differences in outcomes noted between our observations and previously published work exploring the role of ivabradine in patients with heart failure with preserved ejection fraction (HFpEF).1

We acknowledge the central issue: namely, the heterogeneity of patients recruited related to the lack of clear consensus regarding the pathophysiology of HFpEF and the inability of traditional diagnostic techniques, such as resting echocardiography, to diagnose this condition.
Original languageEnglish
Pages (from-to)e604
JournalCirculation
Volume133
Issue number16
DOIs
Publication statusPublished - 19 Apr 2016

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ASJC Scopus subject areas

  • Physiology (medical)
  • Cardiology and Cardiovascular Medicine

Cite this

Pal, N., Sivaswamy, N., Mahmod, M., Yavari, A., Rudd, A., Singh, S., Dawson, D. K., Francis, J. M., Dwight, J. S., Watkins, H., Neubauer, S., Frenneaux, M., & Ashrafian, H. (2016). Response to Letter Regarding Article, "the Effect of Selective Heart Rate Slowing in Heart Failure with Preserved Ejection Fraction". Circulation, 133(16), e604. https://doi.org/10.1161/CIRCULATIONAHA.116.021488