Retinal vascular geometry: Examination of the changes between the early stages of diabetes and first year of diabetic retinopathy

Georgios Leontidis*, Bashir Al-Diri, Andrew Hunter

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingPublished conference contribution

1 Citation (Scopus)

Abstract

Controversy exists on how the functional impairment triggered by diabetes affects the retinal vascular structure, leading to diabetic retinopathy (DR). DR remains a main cause of blindness in United Kingdom with thousands of new cases per year. Diagnosing DR early is crucial for planning the treatment more effectively, before the retina of the eye is severely affected. In this study we investigated the hypothesis that significant vascular changes occur during the progression of diabetes until the first lesions appear in the retina (background retinopathy). The analysis is approached from a novel perspective in which the selected images for pre-/post-DR come from the same patients who have progressed from diabetes to DR. The measurements were analyzed using a statistical model. Veins' and arteries' widths and also arteries' angles were found to differ significantly between the two cases, but no statistical significance was observed for the veins' angles.

Original languageEnglish
Title of host publicationProceedings of the 2015 Science and Information Conference, SAI 2015
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages709-713
Number of pages5
ISBN (Electronic)9781479985470
DOIs
Publication statusPublished - 2 Sept 2015
EventScience and Information Conference, SAI 2015 - London, United Kingdom
Duration: 28 Jul 201530 Jul 2015

Publication series

NameProceedings of the 2015 Science and Information Conference, SAI 2015

Conference

ConferenceScience and Information Conference, SAI 2015
Country/TerritoryUnited Kingdom
CityLondon
Period28/07/1530/07/15

Bibliographical note

ACKNOWLEDGMENT: Special thanks to Greg Russell and Evi kotsiliti from the Health Intelligence company in UK for their support in providing images for analysis as well as Phil Assheton for his advice on improving the analysis.

Keywords

  • Diabetes
  • Diabetic retinopathy
  • Progress
  • Retina
  • Vasculature

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