Rice-arsenate interactions in hydroponics: a three-gene model for tolerance

Gareth John Norton, Meher Nigar, Paul Nicholas Williams, Tapash Dasgupta, Andrew Alexander Meharg, Adam Huw Price

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

In this study, the genetic mapping of the tolerance of root growth to 13.3 mu M arsenate [As(V)] using the BalaxAzucena population is improved, and candidate genes for further study are identified. A remarkable three-gene model of tolerance is advanced, which appears to involve epistatic interaction between three major genes, two on chromosome 6 and one on chromosome 10. Any combination of two of these genes inherited from the tolerant parent leads to the plant having tolerance. Lists of potential positional candidate genes are presented. These are then refined using whole genome transcriptomics data and bioinformatics. Physiological evidence is also provided that genes related to phosphate transport are unlikely to be behind the genetic loci conferring tolerance. These results offer testable hypotheses for genes related to As(V) tolerance that might offer strategies for mitigating arsenic (As) accumulation in consumed rice.

Original languageEnglish
Pages (from-to)2277-2284
Number of pages8
JournalJournal of Experimental Botany
Volume59
Issue number8
DOIs
Publication statusPublished - May 2008

Keywords

  • arsenate tolerance
  • candidate genes
  • epistatic interactions
  • Oryza sativa
  • oryza-sativa
  • phytochelatin complexes
  • holcus-lanatus
  • polymorphism
  • metabolism
  • arsenite
  • roots
  • gene
  • map
  • Arsenate tolerance

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