TY - JOUR
T1 - Risk factors in the development of Kaposis sarcoma
AU - Colman, Rachel
AU - Blackbourn, David J.
N1 - Acknowledgements
Research in D.J.B.'s laboratory is currently funded by Cancer Research UK and the Medical Research Council.
PY - 2008/8/20
Y1 - 2008/8/20
N2 - Kaposi's sarcoma is a multifocal malignancy observed in elderly Mediterranean men (so-called Classic Kaposi's sarcoma), individuals in Africa (endemic Kaposi's sarcoma) and patients with immune disorders, including those undergoing organ transplantation (iatrogenic Kaposi's sarcoma) or infected with HIV (epidemic Kaposi's sarcoma). In all of these four clinical categories of Kaposi's sarcoma, the tumour represents aberrant angiogenesis or lymphangiogenesis (i.e. formation of new blood or lymphatic vessels, respectively [1]) through proliferation of spindle-shaped endothelial cells that line these vascular structures.
AB - Kaposi's sarcoma is a multifocal malignancy observed in elderly Mediterranean men (so-called Classic Kaposi's sarcoma), individuals in Africa (endemic Kaposi's sarcoma) and patients with immune disorders, including those undergoing organ transplantation (iatrogenic Kaposi's sarcoma) or infected with HIV (epidemic Kaposi's sarcoma). In all of these four clinical categories of Kaposi's sarcoma, the tumour represents aberrant angiogenesis or lymphangiogenesis (i.e. formation of new blood or lymphatic vessels, respectively [1]) through proliferation of spindle-shaped endothelial cells that line these vascular structures.
UR - http://www.scopus.com/inward/record.url?scp=52249104191&partnerID=8YFLogxK
U2 - 10.1097/QAD.0b013e3283031a9f
DO - 10.1097/QAD.0b013e3283031a9f
M3 - Editorial
C2 - 18670223
AN - SCOPUS:52249104191
VL - 22
SP - 1629
EP - 1632
JO - AIDS
JF - AIDS
SN - 0269-9370
IS - 13
ER -
