Rotavirus gastroenteritis and central nervous system (CNS) infection: characterization of the VP7 and VP4 genes of rotavirus strains isolated from paired fecal and cerebrospinal fluid samples from a child with CNS disease

M. Iturriza-Gomara, Ian A Auchterlonie, Win Zaw, P. Molyneaux, U. Desselberger, J. Gray

    Research output: Contribution to journalArticle

    54 Citations (Scopus)

    Abstract

    Rotavirus RNA was detected in the cerebrospinal fluid (CSF) of a child with central nervous system disease symptoms associated with rotavirus gastroenteritis. The rotavirus isolates from the fecal and CSF samples were genotyped as G1P[8]. Sequence analysis of the VP7 and VP4 proteins derived from the fecal and CSF samples were remarkably similar to each other and to G1P[8] rotavirus strains commonly circulating in the community and associated with gastroenteritis.

    Original languageEnglish
    Pages (from-to)4797-4799
    Number of pages2
    JournalJournal of Clinical Microbiology
    Volume40
    Issue number12
    DOIs
    Publication statusPublished - 2002

    Keywords

    • POLYMERASE-CHAIN-REACTION
    • REVERSE TRANSCRIPTION
    • ENCEPHALOPATHY
    • ENCEPHALITIS
    • CONVULSIONS
    • DIVERSITY
    • SYMPTOMS
    • NEURONS
    • AXONS
    • PCR

    Cite this

    Rotavirus gastroenteritis and central nervous system (CNS) infection: characterization of the VP7 and VP4 genes of rotavirus strains isolated from paired fecal and cerebrospinal fluid samples from a child with CNS disease. / Iturriza-Gomara, M.; Auchterlonie, Ian A; Zaw, Win; Molyneaux, P.; Desselberger, U.; Gray, J.

    In: Journal of Clinical Microbiology, Vol. 40, No. 12, 2002, p. 4797-4799.

    Research output: Contribution to journalArticle

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    abstract = "Rotavirus RNA was detected in the cerebrospinal fluid (CSF) of a child with central nervous system disease symptoms associated with rotavirus gastroenteritis. The rotavirus isolates from the fecal and CSF samples were genotyped as G1P[8]. Sequence analysis of the VP7 and VP4 proteins derived from the fecal and CSF samples were remarkably similar to each other and to G1P[8] rotavirus strains commonly circulating in the community and associated with gastroenteritis.",
    keywords = "POLYMERASE-CHAIN-REACTION, REVERSE TRANSCRIPTION, ENCEPHALOPATHY, ENCEPHALITIS, CONVULSIONS, DIVERSITY, SYMPTOMS, NEURONS, AXONS, PCR",
    author = "M. Iturriza-Gomara and Auchterlonie, {Ian A} and Win Zaw and P. Molyneaux and U. Desselberger and J. Gray",
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    AU - Iturriza-Gomara, M.

    AU - Auchterlonie, Ian A

    AU - Zaw, Win

    AU - Molyneaux, P.

    AU - Desselberger, U.

    AU - Gray, J.

    PY - 2002

    Y1 - 2002

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    KW - POLYMERASE-CHAIN-REACTION

    KW - REVERSE TRANSCRIPTION

    KW - ENCEPHALOPATHY

    KW - ENCEPHALITIS

    KW - CONVULSIONS

    KW - DIVERSITY

    KW - SYMPTOMS

    KW - NEURONS

    KW - AXONS

    KW - PCR

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