Rule-abstraction deficits following a basal ganglia lesion

Rachel Swainson, T W Robbins

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The cognitive profile of a patient, PM, who had damage to the right basal ganglia as the result of a stroke was investigated. Whilst most cognitive functions were intact, she showed specific neuropsychological deficits, most notably a difficulty in developing, through abstraction of the relevant information, a higher-level rule by which to guide behaviour. The types of rule affected were those based upon an attentional set (attending to a particular dimension of stimulus features, such as 'shape') or a response strategy (continuing to apply a previously successful pattern of responses). The learning of lower-level rules based on stimulus-reward values was spared, as was the ability to apply an instructed rule and to discontinue use of rules which were no longer appropriate. These data provide evidence for the dissociability of cognitive functions within the basal ganglia.

Original languageEnglish
Pages (from-to)433-444
Number of pages12
JournalNeurocase
Volume7
Issue number5
Publication statusPublished - 2001

Keywords

  • TEMPORAL-LOBE EXCISIONS
  • PARKINSONS-DISEASE
  • HUNTINGTONS-DISEASE
  • COGNITIVE DEFICITS
  • WORKING-MEMORY
  • AMYGDALO-HIPPOCAMPECTOMY
  • ALZHEIMERS-DISEASE
  • MNEMONIC FUNCTIONS
  • TEST-PERFORMANCE
  • MECHANISMS

Cite this

Rule-abstraction deficits following a basal ganglia lesion. / Swainson, Rachel; Robbins, T W .

In: Neurocase, Vol. 7, No. 5, 2001, p. 433-444.

Research output: Contribution to journalArticle

Swainson, R & Robbins, TW 2001, 'Rule-abstraction deficits following a basal ganglia lesion', Neurocase, vol. 7, no. 5, pp. 433-444.
Swainson, Rachel ; Robbins, T W . / Rule-abstraction deficits following a basal ganglia lesion. In: Neurocase. 2001 ; Vol. 7, No. 5. pp. 433-444.
@article{c140207ae8844080a0aaf496c47b93d9,
title = "Rule-abstraction deficits following a basal ganglia lesion",
abstract = "The cognitive profile of a patient, PM, who had damage to the right basal ganglia as the result of a stroke was investigated. Whilst most cognitive functions were intact, she showed specific neuropsychological deficits, most notably a difficulty in developing, through abstraction of the relevant information, a higher-level rule by which to guide behaviour. The types of rule affected were those based upon an attentional set (attending to a particular dimension of stimulus features, such as 'shape') or a response strategy (continuing to apply a previously successful pattern of responses). The learning of lower-level rules based on stimulus-reward values was spared, as was the ability to apply an instructed rule and to discontinue use of rules which were no longer appropriate. These data provide evidence for the dissociability of cognitive functions within the basal ganglia.",
keywords = "TEMPORAL-LOBE EXCISIONS, PARKINSONS-DISEASE, HUNTINGTONS-DISEASE, COGNITIVE DEFICITS, WORKING-MEMORY, AMYGDALO-HIPPOCAMPECTOMY, ALZHEIMERS-DISEASE, MNEMONIC FUNCTIONS, TEST-PERFORMANCE, MECHANISMS",
author = "Rachel Swainson and Robbins, {T W}",
year = "2001",
language = "English",
volume = "7",
pages = "433--444",
journal = "Neurocase",
issn = "1355-4794",
publisher = "Psychology Press Ltd",
number = "5",

}

TY - JOUR

T1 - Rule-abstraction deficits following a basal ganglia lesion

AU - Swainson, Rachel

AU - Robbins, T W

PY - 2001

Y1 - 2001

N2 - The cognitive profile of a patient, PM, who had damage to the right basal ganglia as the result of a stroke was investigated. Whilst most cognitive functions were intact, she showed specific neuropsychological deficits, most notably a difficulty in developing, through abstraction of the relevant information, a higher-level rule by which to guide behaviour. The types of rule affected were those based upon an attentional set (attending to a particular dimension of stimulus features, such as 'shape') or a response strategy (continuing to apply a previously successful pattern of responses). The learning of lower-level rules based on stimulus-reward values was spared, as was the ability to apply an instructed rule and to discontinue use of rules which were no longer appropriate. These data provide evidence for the dissociability of cognitive functions within the basal ganglia.

AB - The cognitive profile of a patient, PM, who had damage to the right basal ganglia as the result of a stroke was investigated. Whilst most cognitive functions were intact, she showed specific neuropsychological deficits, most notably a difficulty in developing, through abstraction of the relevant information, a higher-level rule by which to guide behaviour. The types of rule affected were those based upon an attentional set (attending to a particular dimension of stimulus features, such as 'shape') or a response strategy (continuing to apply a previously successful pattern of responses). The learning of lower-level rules based on stimulus-reward values was spared, as was the ability to apply an instructed rule and to discontinue use of rules which were no longer appropriate. These data provide evidence for the dissociability of cognitive functions within the basal ganglia.

KW - TEMPORAL-LOBE EXCISIONS

KW - PARKINSONS-DISEASE

KW - HUNTINGTONS-DISEASE

KW - COGNITIVE DEFICITS

KW - WORKING-MEMORY

KW - AMYGDALO-HIPPOCAMPECTOMY

KW - ALZHEIMERS-DISEASE

KW - MNEMONIC FUNCTIONS

KW - TEST-PERFORMANCE

KW - MECHANISMS

M3 - Article

VL - 7

SP - 433

EP - 444

JO - Neurocase

JF - Neurocase

SN - 1355-4794

IS - 5

ER -