Schistosoma mansoni: Uptake in vitro and incorporation of adenine by adults

Julian G. Mercer*, Leslie H. Chappell

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


The rates of adenine uptake and incorporation into nucleic acids by adult male and female Schistosoma mansoni were determined during periods of up to 10 days in vitro, and comparisons were made between paired and separated worms. Adenine uptake by separated males and females exceeded that exhibited by equivalent paired worms. The rate of incorporation of adenine into nucleic acids was higher in separated females than in paired females. In contrast, the state of pairing had little effect on adenine incorporation by male S. mansoni. There was no correlation between rates of adenine uptake and incorporation and the reproductive activity of S. mansoni adults in vitro. Uptake and incorporation rates appeared to reflect the changing somatic requirements of both male and female worms.

Original languageEnglish
Pages (from-to)438-444
Number of pages7
JournalExperimental Parasitology
Issue number3
Publication statusPublished - Jun 1986


  • Adenine uptake
  • Blood fluke
  • Culture in vitro
  • Incorporation
  • Pairing
  • Schistosoma mansoni
  • Trematode, digenetic


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