Screening of the central nervous system in children with invasive pulmonary aspergillosis

Emmi Broenen, Annelies Mavinkurve-Groothuis, Karin Kamphuis-van Ulzen, Roger Brüggemann, Paul Verweij, Adilia Warris

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)
4 Downloads (Pure)

Abstract

The existing guidelines regarding the management of invasive pulmonary aspergillosis do not recommend screening of the extra-pulmonary sites. Due to the fact that the presence of central nervous system (CNS) aspergillosis will influence treatment decisions regarding which antifungal to use and the aimed target concentrations of azoles in plasma, to be informed about dissemination of the infection to the CNS is absolutely necessary. We demonstrate the need for a structured approach to screening of pediatric patients for CNS aspergillosis.

Original languageEnglish
Pages (from-to)8-11
Number of pages4
JournalMedical mycology case reports
Volume4
Early online date20 Feb 2014
DOIs
Publication statusPublished - Apr 2014

Keywords

  • Aspergillosis
  • Central nervous system
  • Pediatrics
  • Screening
  • Therapeutic drug monitoring
  • Voriconazole

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