Seasonal 25-hydroxyvitamin D changes in British postmenopausal women at 57 degrees N and 51 degrees N

Alexandra Mavroeidi, F O'Neill, P A Lee, A L Darling, W D Fraser, J L Berry, W T Lee, David M Reid, S A Lanham-New, Helen Margaret Macdonald

Research output: Contribution to journalArticle

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Abstract

The UK has insufficient intensity of sunlight at wavelengths 290-315nm to enable cutaneous synthesis of vitamin D from October to April. There are regional differences in UVB strength throughout the UK but whether this translates to differences in vitamin D status is not known. We have reported seasonal variations in a cross-sectional study of over 3000 Scottish women in Aberdeen. The aim of this longitudinal study was to compare the seasonal variation of serum 25-hydroxyvitamin D [25(OH)D] in postmenopausal women residing in Aberdeen (57 degrees N) and Surrey (51 degrees N). Women attended 3-monthly visits over 12 months, starting summer 2006. In Aberdeen, 338 Caucasian women (mean age+/-SD, 61.7+/-1.5 years); and at Surrey, 138 Caucasian women (61.4+/-4.5 years) and 35 Asian women (59.9+/-6.4 years) had serum 25(OH)D measured by IDS enzyme immunoassay. In winter/spring none of the Caucasian women living in Surrey had 25(OH)D
Original languageEnglish
Pages (from-to)459-461
Number of pages3
JournalThe Journal of Steroid Biochemistry and Molecular Biology
Volume121
Issue number1-2
Early online date17 Mar 2010
DOIs
Publication statusPublished - Jul 2010

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Vitamin D
Wavelength
Enzymes
Sunlight
25-hydroxyvitamin D
Serum
Immunoenzyme Techniques
Longitudinal Studies
Cross-Sectional Studies
Skin

Keywords

  • Vitamin D deficiency
  • Seasonal variation
  • Regional UK variation
  • Asian vs. Caucasian postmenopausal women
  • Longitudinal study

Cite this

Seasonal 25-hydroxyvitamin D changes in British postmenopausal women at 57 degrees N and 51 degrees N. / Mavroeidi, Alexandra; O'Neill, F; Lee, P A; Darling, A L; Fraser, W D; Berry, J L; Lee, W T; Reid, David M; Lanham-New, S A; Macdonald, Helen Margaret.

In: The Journal of Steroid Biochemistry and Molecular Biology, Vol. 121, No. 1-2, 07.2010, p. 459-461.

Research output: Contribution to journalArticle

Mavroeidi, A, O'Neill, F, Lee, PA, Darling, AL, Fraser, WD, Berry, JL, Lee, WT, Reid, DM, Lanham-New, SA & Macdonald, HM 2010, 'Seasonal 25-hydroxyvitamin D changes in British postmenopausal women at 57 degrees N and 51 degrees N' The Journal of Steroid Biochemistry and Molecular Biology, vol. 121, no. 1-2, pp. 459-461. https://doi.org/10.1016/j.jsbmb.2010.03.038
Mavroeidi, Alexandra ; O'Neill, F ; Lee, P A ; Darling, A L ; Fraser, W D ; Berry, J L ; Lee, W T ; Reid, David M ; Lanham-New, S A ; Macdonald, Helen Margaret. / Seasonal 25-hydroxyvitamin D changes in British postmenopausal women at 57 degrees N and 51 degrees N. In: The Journal of Steroid Biochemistry and Molecular Biology. 2010 ; Vol. 121, No. 1-2. pp. 459-461.
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