Seasonal pattern in admissions and mortality from acute myocardial infarction in elderly patients in Isfahan, Iran

Abdollah Mohammadian-Hafshejani, Nizal Sarrafzadegan, Shidokht Hosseini, Hamid Reza Baradaran, Hamidreza Roohafza, Masoumeh Sadeghi, Mohsen Asadi-Lari* (Corresponding Author)

*Corresponding author for this work

Research output: Contribution to journalArticle

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Abstract

BACKGROUND: Seasonal variation in admissions and mortality due to acute myocardial infarction has been observed in different countries. Since there are scarce reports about this variation in Iran, this study was carried out to determine the existence of seasonal rhythms in hospital admissions for acute myocardial infarction, and in mortality due to AMI in elderly patients in Isfahan city. METHODS: This prospective hospital-based study included a total of 3990 consecutive patients with acute myocardial infarction admitted to 13 hospitals from January 2002 to December 2007. Seasonal variations were analyzed with the Kaplan-Meier table, log rank test, and Cox regression model. RESULTS: There was a statistically significant relationship between the occurrence of heart disease based on season and type of acute myocardial infarction anatomical (P < 0.001). The relationship between the occurrence of death and season and type of acute myocardial infarction (AMI) according to International Classification of Diseases code 10 (ICD) was also observed and it was statistically significant (P = 0.026). Hazard ratio for death from acute myocardial infarction were 0.96 [Confidence interval of 95% (95% CI) = 0.78-1.18], 0.9 (95%CI = 0.73-1.11), and 1.04 (95%CI = 0.85-1.26) during spring, summer, and winter, respectively. CONCLUSION: There is seasonal variation in hospital admission and mortality due to AMI; however, after adjusting in the model only gender and age were significant predictor factors.

Original languageEnglish
Pages (from-to)46-54
Number of pages9
JournalARYA Atherosclerosis
Volume10
Issue number1
Publication statusPublished - 14 Jan 2014

Fingerprint

Iran
Myocardial Infarction
Mortality
International Classification of Diseases
Hospital Mortality
Proportional Hazards Models
Heart Diseases
Confidence Intervals

Keywords

  • Acute myocardial infarction
  • Admission in hospital
  • Isfahan
  • Mortality
  • Season

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Mohammadian-Hafshejani, A., Sarrafzadegan, N., Hosseini, S., Reza Baradaran, H., Roohafza, H., Sadeghi, M., & Asadi-Lari, M. (2014). Seasonal pattern in admissions and mortality from acute myocardial infarction in elderly patients in Isfahan, Iran. ARYA Atherosclerosis, 10(1), 46-54.

Seasonal pattern in admissions and mortality from acute myocardial infarction in elderly patients in Isfahan, Iran. / Mohammadian-Hafshejani, Abdollah; Sarrafzadegan, Nizal; Hosseini, Shidokht; Reza Baradaran, Hamid; Roohafza, Hamidreza; Sadeghi, Masoumeh; Asadi-Lari, Mohsen (Corresponding Author).

In: ARYA Atherosclerosis, Vol. 10, No. 1, 14.01.2014, p. 46-54.

Research output: Contribution to journalArticle

Mohammadian-Hafshejani, A, Sarrafzadegan, N, Hosseini, S, Reza Baradaran, H, Roohafza, H, Sadeghi, M & Asadi-Lari, M 2014, 'Seasonal pattern in admissions and mortality from acute myocardial infarction in elderly patients in Isfahan, Iran', ARYA Atherosclerosis, vol. 10, no. 1, pp. 46-54.
Mohammadian-Hafshejani A, Sarrafzadegan N, Hosseini S, Reza Baradaran H, Roohafza H, Sadeghi M et al. Seasonal pattern in admissions and mortality from acute myocardial infarction in elderly patients in Isfahan, Iran. ARYA Atherosclerosis. 2014 Jan 14;10(1):46-54.
Mohammadian-Hafshejani, Abdollah ; Sarrafzadegan, Nizal ; Hosseini, Shidokht ; Reza Baradaran, Hamid ; Roohafza, Hamidreza ; Sadeghi, Masoumeh ; Asadi-Lari, Mohsen. / Seasonal pattern in admissions and mortality from acute myocardial infarction in elderly patients in Isfahan, Iran. In: ARYA Atherosclerosis. 2014 ; Vol. 10, No. 1. pp. 46-54.
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abstract = "BACKGROUND: Seasonal variation in admissions and mortality due to acute myocardial infarction has been observed in different countries. Since there are scarce reports about this variation in Iran, this study was carried out to determine the existence of seasonal rhythms in hospital admissions for acute myocardial infarction, and in mortality due to AMI in elderly patients in Isfahan city. METHODS: This prospective hospital-based study included a total of 3990 consecutive patients with acute myocardial infarction admitted to 13 hospitals from January 2002 to December 2007. Seasonal variations were analyzed with the Kaplan-Meier table, log rank test, and Cox regression model. RESULTS: There was a statistically significant relationship between the occurrence of heart disease based on season and type of acute myocardial infarction anatomical (P < 0.001). The relationship between the occurrence of death and season and type of acute myocardial infarction (AMI) according to International Classification of Diseases code 10 (ICD) was also observed and it was statistically significant (P = 0.026). Hazard ratio for death from acute myocardial infarction were 0.96 [Confidence interval of 95{\%} (95{\%} CI) = 0.78-1.18], 0.9 (95{\%}CI = 0.73-1.11), and 1.04 (95{\%}CI = 0.85-1.26) during spring, summer, and winter, respectively. CONCLUSION: There is seasonal variation in hospital admission and mortality due to AMI; however, after adjusting in the model only gender and age were significant predictor factors.",
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AU - Hosseini, Shidokht

AU - Reza Baradaran, Hamid

AU - Roohafza, Hamidreza

AU - Sadeghi, Masoumeh

AU - Asadi-Lari, Mohsen

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AB - BACKGROUND: Seasonal variation in admissions and mortality due to acute myocardial infarction has been observed in different countries. Since there are scarce reports about this variation in Iran, this study was carried out to determine the existence of seasonal rhythms in hospital admissions for acute myocardial infarction, and in mortality due to AMI in elderly patients in Isfahan city. METHODS: This prospective hospital-based study included a total of 3990 consecutive patients with acute myocardial infarction admitted to 13 hospitals from January 2002 to December 2007. Seasonal variations were analyzed with the Kaplan-Meier table, log rank test, and Cox regression model. RESULTS: There was a statistically significant relationship between the occurrence of heart disease based on season and type of acute myocardial infarction anatomical (P < 0.001). The relationship between the occurrence of death and season and type of acute myocardial infarction (AMI) according to International Classification of Diseases code 10 (ICD) was also observed and it was statistically significant (P = 0.026). Hazard ratio for death from acute myocardial infarction were 0.96 [Confidence interval of 95% (95% CI) = 0.78-1.18], 0.9 (95%CI = 0.73-1.11), and 1.04 (95%CI = 0.85-1.26) during spring, summer, and winter, respectively. CONCLUSION: There is seasonal variation in hospital admission and mortality due to AMI; however, after adjusting in the model only gender and age were significant predictor factors.

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