Self-regulation and the foraging gene (PRKG1) in humans

Andriy A. Struk, Jhotisha Mugon, Andrea Huston, Abigail A. Scholer, Gertraud Stadler, E. Tory Higgins, Marla B. Sokolowski, James Danckert (Corresponding Author)

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Foraging is a goal-directed behaviour that balances the need to explore the environment for resources with the need to exploit those resources. In Drosophila melanogaster distinct phenotypes have been observed in relation to the foraging gene (for), labelled the rover and sitter. Adult rovers explore their environs more extensively than do adult sitters. We explored whether this distinction would be conserved in humans. We made use of a distinction from Regulatory Mode Theory between those who ‘get on with it’–so-called Locomotors, and those who prefer to ensure they ‘do the right thing’, so-called Assessors. In this logic, rovers and Locomotors share similarities in goal pursuit, as do sitters and Assessors. In two samples, we show that genetic variation in PRKG1, the human orthologue of for, is associated with preferential adoption of a specific regulatory mode. Next, participants performed a foraging task to see whether genetic differences associated with distinct regulatory modes would be associated with distinct goal pursuit patterns. Assessors tended to hug the boundary of the foraging environment, much like behaviours seen in Drosophila adult sitters. In a patchy foraging environment, Assessors adopted more cautious search strategies maximising exploitation. These results show that distinct patterns of goal pursuit are associated with particular genotypes of PRKG1, the human orthologue of for.
Original languageEnglish
Pages (from-to)4434-4439
Number of pages6
JournalPNAS
Volume116
Issue number10
Early online date19 Feb 2019
DOIs
Publication statusPublished - 5 Mar 2019

Keywords

  • foraging gene
  • self-regulation
  • locomotion
  • assessment
  • PRKG1
  • Locomotion
  • Assessment
  • Foraging gene
  • Self-regulation

ASJC Scopus subject areas

  • General

Fingerprint Dive into the research topics of 'Self-regulation and the <i>foraging </i>gene (<i>PRKG1</i>) in humans'. Together they form a unique fingerprint.

  • Cite this

    Struk, A. A., Mugon, J., Huston, A., Scholer, A. A., Stadler, G., Higgins, E. T., Sokolowski, M. B., & Danckert, J. (2019). Self-regulation and the foraging gene (PRKG1) in humans. PNAS, 116(10), 4434-4439. https://doi.org/10.1073/pnas.1809924116