Self-reported pain severity is associated with a history of coronary heart disease

S. Parsons; J. McBeth; G. J. Macfarlane; P. C. Hannaford; D. P. M. Symmons

doi:10.1002/ejp.533

Self-reported pain severity is associated with a history of coronary heart disease

S. Parsons, J. McBeth, G. J. Macfarlane, P. C. Hannaford, D. P. M. Symmons

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Abstract

Background
Previous studies have found an association between chronic pain and cardiovascular (CV) mortality.

Objective
To explore the relationship between the severity of pain and non-fatal CV disease.

Methods
A total of 45,994 adults randomly selected from general practice registers in Manchester and Aberdeen were posted a survey, which included a Chronic Pain Grade questionnaire, pain manikin and questions about lifestyle and medical history. A single component measuring pain severity was extracted using factor analysis. Logistic regression was used to test for an association between quintiles of pain severity and a history of CV disease, adjusting for confounders.

Results
Of the 15,288 responders, 61% (n = 9357) reported pain for ≥1 day in the past month. Compared with the first (lowest) pain severity quintile, the fully adjusted odds ratio for heart attack in the second severity quintile was 1.25 (95% confidence interval 0.68, 2.30); third quintile: 1.65 (0.93, 2.94); fourth quintile: 1.76 (1.00, 3.11) and fifth (highest) quintile 2.47 (1.43, 4.28). Corresponding figures for angina (excluding heart attack) were: 1.79 (0.93, 3.45), 1.91 (1.00, 3.62), 1.03 (0.50, 2.11) and 3.17 (1.71, 5.85).

Conclusion
A history of CV disease is reported more often in those with severe pain than would be expected by chance, even when adjusting for shared risk factors.

Original language	English
Pages (from-to)	167-175
Number of pages	9
Journal	European Journal of Pain
Volume	19
Issue number	2
Early online date	28 May 2014
DOIs	https://doi.org/10.1002/ejp.533
Publication status	Published - Feb 2015

Bibliographical note

This study was funded by Arthritis Research UK (grant number: 17292).

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Cite this

@article{5cfcbbafddd9460ca6b63958270c9fd8,

title = "Self-reported pain severity is associated with a history of coronary heart disease",

abstract = "BackgroundPrevious studies have found an association between chronic pain and cardiovascular (CV) mortality.ObjectiveTo explore the relationship between the severity of pain and non-fatal CV disease.MethodsA total of 45,994 adults randomly selected from general practice registers in Manchester and Aberdeen were posted a survey, which included a Chronic Pain Grade questionnaire, pain manikin and questions about lifestyle and medical history. A single component measuring pain severity was extracted using factor analysis. Logistic regression was used to test for an association between quintiles of pain severity and a history of CV disease, adjusting for confounders.ResultsOf the 15,288 responders, 61% (n = 9357) reported pain for ≥1 day in the past month. Compared with the first (lowest) pain severity quintile, the fully adjusted odds ratio for heart attack in the second severity quintile was 1.25 (95% confidence interval 0.68, 2.30); third quintile: 1.65 (0.93, 2.94); fourth quintile: 1.76 (1.00, 3.11) and fifth (highest) quintile 2.47 (1.43, 4.28). Corresponding figures for angina (excluding heart attack) were: 1.79 (0.93, 3.45), 1.91 (1.00, 3.62), 1.03 (0.50, 2.11) and 3.17 (1.71, 5.85).ConclusionA history of CV disease is reported more often in those with severe pain than would be expected by chance, even when adjusting for shared risk factors.",

author = "S. Parsons and J. McBeth and Macfarlane, {G. J.} and Hannaford, {P. C.} and Symmons, {D. P. M.}",

note = "This study was funded by Arthritis Research UK (grant number: 17292).",

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doi = "10.1002/ejp.533",

language = "English",

volume = "19",

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T1 - Self-reported pain severity is associated with a history of coronary heart disease

AU - Parsons, S.

AU - McBeth, J.

AU - Macfarlane, G. J.

AU - Hannaford, P. C.

AU - Symmons, D. P. M.

N1 - This study was funded by Arthritis Research UK (grant number: 17292).

PY - 2015/2

Y1 - 2015/2

N2 - BackgroundPrevious studies have found an association between chronic pain and cardiovascular (CV) mortality.ObjectiveTo explore the relationship between the severity of pain and non-fatal CV disease.MethodsA total of 45,994 adults randomly selected from general practice registers in Manchester and Aberdeen were posted a survey, which included a Chronic Pain Grade questionnaire, pain manikin and questions about lifestyle and medical history. A single component measuring pain severity was extracted using factor analysis. Logistic regression was used to test for an association between quintiles of pain severity and a history of CV disease, adjusting for confounders.ResultsOf the 15,288 responders, 61% (n = 9357) reported pain for ≥1 day in the past month. Compared with the first (lowest) pain severity quintile, the fully adjusted odds ratio for heart attack in the second severity quintile was 1.25 (95% confidence interval 0.68, 2.30); third quintile: 1.65 (0.93, 2.94); fourth quintile: 1.76 (1.00, 3.11) and fifth (highest) quintile 2.47 (1.43, 4.28). Corresponding figures for angina (excluding heart attack) were: 1.79 (0.93, 3.45), 1.91 (1.00, 3.62), 1.03 (0.50, 2.11) and 3.17 (1.71, 5.85).ConclusionA history of CV disease is reported more often in those with severe pain than would be expected by chance, even when adjusting for shared risk factors.

AB - BackgroundPrevious studies have found an association between chronic pain and cardiovascular (CV) mortality.ObjectiveTo explore the relationship between the severity of pain and non-fatal CV disease.MethodsA total of 45,994 adults randomly selected from general practice registers in Manchester and Aberdeen were posted a survey, which included a Chronic Pain Grade questionnaire, pain manikin and questions about lifestyle and medical history. A single component measuring pain severity was extracted using factor analysis. Logistic regression was used to test for an association between quintiles of pain severity and a history of CV disease, adjusting for confounders.ResultsOf the 15,288 responders, 61% (n = 9357) reported pain for ≥1 day in the past month. Compared with the first (lowest) pain severity quintile, the fully adjusted odds ratio for heart attack in the second severity quintile was 1.25 (95% confidence interval 0.68, 2.30); third quintile: 1.65 (0.93, 2.94); fourth quintile: 1.76 (1.00, 3.11) and fifth (highest) quintile 2.47 (1.43, 4.28). Corresponding figures for angina (excluding heart attack) were: 1.79 (0.93, 3.45), 1.91 (1.00, 3.62), 1.03 (0.50, 2.11) and 3.17 (1.71, 5.85).ConclusionA history of CV disease is reported more often in those with severe pain than would be expected by chance, even when adjusting for shared risk factors.

U2 - 10.1002/ejp.533

DO - 10.1002/ejp.533

M3 - Article

SN - 1090-3801

VL - 19

SP - 167

EP - 175

JO - European Journal of Pain

JF - European Journal of Pain

IS - 2

ER -

Self-reported pain severity is associated with a history of coronary heart disease

Abstract

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