Sensitivity and responsiveness of the patient-reported TED-QOL to rehabilitative surgery in thyroid eye disease

Tessa Fayers, Peter M. Fayers, Peter J. Dolman* (Corresponding Author)

*Corresponding author for this work

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We tested the sensitivity and responsiveness of the TED-QOL to rehabilitative surgery in thyroid eye disease (TED). The 3-item TED-QOL and 16-item GO-QOL, which assess quality of life (QoL) in TED, were administered to consecutive patients undergoing rehabilitative surgery. The questionnaires were completed pre-and post-operatively to assess sensitivity (ability to discriminate between different surgical groups) and responsiveness (ability to detect within patient changes over time).56 patients underwent 69 procedures for TED (29 orbital decompressions, 15 strabismus operations, 25 eyelid procedures). The differences in scores between the three types of surgery (a measure of sensitivity) were statistically significant at the 5% level pre-operatively and post-operatively for all 3 TED-QOL scales and for both GO-QOL scales, but much more so for the TED-QOL scales in each case. The within-patient changes between the pre- and post-operative scores for the same subjects (a measure of responsiveness) were statistically very highly significant for the TED-QOL overall and appearance scales for each of the surgeries. The pre- and post-operative difference for the TED-QOL functioning scale was highly statistically significant for strabismus surgery but not for decompression or lid surgery. The change between the pre- and post-operative scores for the GO-QOL was significant for the functioning scale with strabismus and lid surgery, and was highly significant for the appearance scale with lid surgery but not for strabismus surgery or decompression. The 3-item TED-QOL is sensitive and responsive to rehabilitative surgery in TED and compares favorably with the lengthier GO-QOL for these parameters.

Original languageEnglish
Pages (from-to)328-334
Number of pages7
JournalOrbit
Volume35
Issue number6
Early online date16 Sep 2016
DOIs
Publication statusPublished - 2016

Fingerprint

Eye Diseases
Thyroid Diseases
Strabismus
Decompression
Eyelids
Quality of Life

Keywords

  • Graves ophthalmopathy
  • quality of life
  • thyroid eye disease

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Sensitivity and responsiveness of the patient-reported TED-QOL to rehabilitative surgery in thyroid eye disease. / Fayers, Tessa; Fayers, Peter M.; Dolman, Peter J. (Corresponding Author).

In: Orbit, Vol. 35, No. 6, 2016, p. 328-334.

Research output: Contribution to journalArticle

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