SERRS immunoassay for quantitative human CRP analysis

Fiona Margaret Campbell, Andrew Ingram, Paul Monaghan, Jon Cooper, Naveed Sattar, P. David Eckersall, Duncan Graham

    Research output: Contribution to journalArticle

    25 Citations (Scopus)

    Abstract

    SERRS has been used for the first time for the measurement of C-reactive protein (CRP) in an immunoassay. CRP, a biological marker for the diagnosis of infection and inflammation, is quantified in an ELISA using conventional reagents, but the usual colorimetric detection step is replaced by SERRS detection, offering improved sensitivity and potential for multiplexing analysis.

    Original languageEnglish
    Pages (from-to)1355-1357
    Number of pages3
    JournalAnalyst
    Volume133
    Issue number10
    Early online date25 Jun 2008
    DOIs
    Publication statusPublished - 1 Oct 2008

    Keywords

    • C-reactive protein
    • resonance-raman-scattering
    • coronary-heart-disease
    • epidemiologic applications
    • cardiovascular-disease
    • spectroscopy
    • inflammation
    • silver
    • nanoparticles
    • association

    Cite this

    Campbell, F. M., Ingram, A., Monaghan, P., Cooper, J., Sattar, N., Eckersall, P. D., & Graham, D. (2008). SERRS immunoassay for quantitative human CRP analysis. Analyst, 133(10), 1355-1357. https://doi.org/10.1039/b808087a