Shotgun Cloning and Heterologous Expression of the Patellamide Gene Cluster as a Strategy to Achieving Sustained Metabolite Production

P. F. Long, W. C. Dunlap, C. N. Battershill, Marcel Jaspars

Research output: Contribution to journalArticle

136 Citations (Scopus)
Original languageEnglish
Pages (from-to)1760-1765
Number of pages6
JournalChemBioChem
Volume6
Issue number6
Early online date29 Jun 2005
DOIs
Publication statusPublished - 7 Oct 2005

Keywords

  • peptides
  • Escherichia coli
  • heterologous expression
  • HPLC-MS
  • natural products
  • patellamides
  • uNCULTIVATED BACTERIAL SYMBIONT
  • ASCIDIAN LISSOCLINUM-PATELLA
  • POLYKETIDE SYNTHASE GENE
  • CYANOBACTERIAL SYMBIONT
  • NONRIBOSOMAL PEPTIDE
  • ESCHERICHIA-COLI
  • CYCLIC-PEPTIDES
  • BIOSYNTHESIS
  • IDENTIFICATION
  • EPOTHILONE

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