Should androgen supplementation be used for poor ovarian response in IVF?

Sesh Kamal Sunkara, Arri Coomarasamy, Wiebke Arlt, Siladitya Bhattacharya

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Poor ovarian response is reported in 9–24% of IVF cycles. Several interventions have been proposed to improve the outcome, although evidence to support these has been scant. There has been interest in the use of adjuvant androgens in this context and a recent worldwide survey showed that nearly a quarter of IVF clinicians used dehydroepiandrosterone (DHEA) in poor responders. We examine the rationale for the use of adjuvant androgens and suggest that the current clinical uncertainty should be addressed by a randomized controlled trial of DHEA in poor responders.
Original languageEnglish
Pages (from-to)637-640
Number of pages4
JournalHuman Reproduction
Volume27
Issue number3
Early online date16 Jan 2012
DOIs
Publication statusPublished - Mar 2012

Keywords

  • poor ovarian response
  • androgens
  • IVF treatment

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