Should linking replace regression when mapping from profile-based measures to preference-based measures?

Peter M. Fayers* (Corresponding Author), Ron D. Hays

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

49 Citations (Scopus)

Abstract

Background

Profile instruments are frequently used to assess health-related quality of life and other patient-reported outcomes. However, preference-based measures are required for health-economic cost-utility evaluations.

Results

Although regression-based approaches are commonly used to map from profile measures to preference measures, we show that this results in biased estimates because of regression to the mean.

Conclusions

Linking (scale-aligning) is proposed as an alternative.

Original languageEnglish
Pages (from-to)261-265
Number of pages5
JournalValue in Health
Volume17
Issue number2
Early online date15 Mar 2014
DOIs
Publication statusPublished - Mar 2014

Bibliographical note

Source of financial support: Ron D. Hays was supported in part by grants from the National Institute on Aging (grant no. P30-AG021684) and the National Institute on Minority Health and Health Disparities (grant no. P20MD000182).

Keywords

  • linking values
  • mapping functions
  • patient-reported outcomes
  • preference-based measures
  • profile instruments
  • scale-aligning
  • test equating

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