Simultaneous Determination of Stable Carbon, Oxygen, and Hydrogen Isotopes in Cellulose

N.J. Loader, F.A. Street-Perrott, T.J. Daley, P.D.M. Hughes, A. Kimak, T. Levanič, G. Mallon, D. Mauquoy, I. Robertson, T.P. Roland, S. van Bellen, M.M. Ziehmer, M. Leuenberger

Research output: Contribution to journalArticlepeer-review

26 Citations (Scopus)


A technological development is described through which the stable carbon-, oxygen-, and nonexchangeable hydrogen-isotopic ratios (δ13C,
δ18O, δ2 H) are determined on a single carbohydrate (cellulose) sample with
precision equivalent to conventional techniques (δ13C 0.15‰, δ18O 0.30‰,
δ2 H 3.0‰). This triple-isotope approach offers significant new research
opportunities, most notably in physiology and medicine, isotope biogeochemistry,
forensic science, and palaeoclimatology, when isotopic analysis of a common sample is desirable or when sample material is limited.
Original languageEnglish
Pages (from-to)376-380
Number of pages5
JournalAnalytical Chemistry
Issue number1
Early online date11 Dec 2014
Publication statusPublished - 2015


  • Hydrogen Isotopes
  • Cellulose


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