SINGLE DOMAIN BINDING MOLECULE

Caroline Barelle; Mischa Muller; Valerie Calabro; Jack Bikker; John Steven; Lioudmila Tchistiakova; Oleg V Kovalenko; Andrea Olland

SINGLE DOMAIN BINDING MOLECULE

Caroline Barelle (Inventor), Mischa Muller (Inventor), Valerie Calabro (Inventor), Jack Bikker (Inventor), John Steven (Inventor), Lioudmila Tchistiakova (Inventor), Oleg V Kovalenko (Inventor), Andrea Olland (Inventor)

Medical Sciences

Research output: Patent

64 Downloads (Pure)

Abstract

The present invention provides a single domain specific binding molecule having the structure FW1-CDR1-FW2-HV2-FW3a-HV4-FW3b-CDR3-FW4 in which the Framework Regions FW1, FW2, FW3a, FW3b, and FW4, the Complementarity Determining Regions CDR1 and CDR3, and the Hypervariable Regions HV2, and HV4 have amino acid sequences as defined which provide a high affinity anti-human serum albumin (HSA) binding domain.

Original language	English
IPC	C07K16/46
Publication status	Published - 14 Nov 2013

Access to Document

US2013302250A1Final published version, 2.45 MBLicence: Unspecified

Cite this

@misc{c58bf2a1ed844cd1bb2c45e503101e35,

title = "SINGLE DOMAIN BINDING MOLECULE",

abstract = "The present invention provides a single domain specific binding molecule having the structure FW1-CDR1-FW2-HV2-FW3a-HV4-FW3b-CDR3-FW4 in which the Framework Regions FW1, FW2, FW3a, FW3b, and FW4, the Complementarity Determining Regions CDR1 and CDR3, and the Hypervariable Regions HV2, and HV4 have amino acid sequences as defined which provide a high affinity anti-human serum albumin (HSA) binding domain.",

author = "Caroline Barelle and Mischa Muller and Valerie Calabro and Jack Bikker and John Steven and Lioudmila Tchistiakova and Kovalenko, {Oleg V} and Andrea Olland",

year = "2013",

month = nov,

day = "14",

language = "English",

type = "Patent",

note = "C07K16/46",

}

TY - PAT

T1 - SINGLE DOMAIN BINDING MOLECULE

AU - Barelle, Caroline

AU - Muller, Mischa

AU - Calabro, Valerie

AU - Bikker, Jack

AU - Steven, John

AU - Tchistiakova, Lioudmila

AU - Kovalenko, Oleg V

AU - Olland, Andrea

PY - 2013/11/14

Y1 - 2013/11/14

N2 - The present invention provides a single domain specific binding molecule having the structure FW1-CDR1-FW2-HV2-FW3a-HV4-FW3b-CDR3-FW4 in which the Framework Regions FW1, FW2, FW3a, FW3b, and FW4, the Complementarity Determining Regions CDR1 and CDR3, and the Hypervariable Regions HV2, and HV4 have amino acid sequences as defined which provide a high affinity anti-human serum albumin (HSA) binding domain.

AB - The present invention provides a single domain specific binding molecule having the structure FW1-CDR1-FW2-HV2-FW3a-HV4-FW3b-CDR3-FW4 in which the Framework Regions FW1, FW2, FW3a, FW3b, and FW4, the Complementarity Determining Regions CDR1 and CDR3, and the Hypervariable Regions HV2, and HV4 have amino acid sequences as defined which provide a high affinity anti-human serum albumin (HSA) binding domain.

UR - https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20131114&DB=EPODOC&locale=en_EP&CC=US&NR=2013302250A1&KC=A1&ND=5

M3 - Patent

ER -

SINGLE DOMAIN BINDING MOLECULE

Abstract

Access to Document

Other files and links

Fingerprint

Cite this