SINGLE DOMAIN BINDING MOLECULE

Caroline Barelle (Inventor), Mischa Muller (Inventor), Valerie Calabro (Inventor), Jack Bikker (Inventor), John Steven (Inventor), Lioudmila Tchistiakova (Inventor), Oleg V Kovalenko (Inventor), Andrea Olland (Inventor)

Research output: Patent

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Abstract

The present invention provides a single domain specific binding molecule having the structure FW1-CDR1-FW2-HV2-FW3a-HV4-FW3b-CDR3-FW4 in which the Framework Regions FW1, FW2, FW3a, FW3b, and FW4, the Complementarity Determining Regions CDR1 and CDR3, and the Hypervariable Regions HV2, and HV4 have amino acid sequences as defined which provide a high affinity anti-human serum albumin (HSA) binding domain.
Original languageEnglish
IPCC07K16/46
Publication statusPublished - 14 Nov 2013

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Complementarity Determining Regions
Patents and inventions
Serum Albumin
Amino Acids
Molecules

Cite this

Barelle, C., Muller, M., Calabro, V., Bikker, J., Steven, J., Tchistiakova, L., ... Olland, A. (2013). IPC No. C07K16/46. SINGLE DOMAIN BINDING MOLECULE.

SINGLE DOMAIN BINDING MOLECULE. / Barelle, Caroline (Inventor); Muller, Mischa (Inventor); Calabro, Valerie (Inventor); Bikker, Jack (Inventor); Steven, John (Inventor); Tchistiakova, Lioudmila (Inventor); Kovalenko, Oleg V (Inventor); Olland, Andrea (Inventor).

IPC No.: C07K16/46.

Research output: Patent

Barelle, C, Muller, M, Calabro, V, Bikker, J, Steven, J, Tchistiakova, L, Kovalenko, OV & Olland, A 2013, SINGLE DOMAIN BINDING MOLECULE, IPC No. C07K16/46.
Barelle C, Muller M, Calabro V, Bikker J, Steven J, Tchistiakova L et al, inventors. SINGLE DOMAIN BINDING MOLECULE. C07K16/46. 2013 Nov 14.
Barelle, Caroline (Inventor) ; Muller, Mischa (Inventor) ; Calabro, Valerie (Inventor) ; Bikker, Jack (Inventor) ; Steven, John (Inventor) ; Tchistiakova, Lioudmila (Inventor) ; Kovalenko, Oleg V (Inventor) ; Olland, Andrea (Inventor). / SINGLE DOMAIN BINDING MOLECULE. IPC No.: C07K16/46.
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AU - Calabro, Valerie

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AU - Tchistiakova, Lioudmila

AU - Kovalenko, Oleg V

AU - Olland, Andrea

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AB - The present invention provides a single domain specific binding molecule having the structure FW1-CDR1-FW2-HV2-FW3a-HV4-FW3b-CDR3-FW4 in which the Framework Regions FW1, FW2, FW3a, FW3b, and FW4, the Complementarity Determining Regions CDR1 and CDR3, and the Hypervariable Regions HV2, and HV4 have amino acid sequences as defined which provide a high affinity anti-human serum albumin (HSA) binding domain.

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