Abstract
Novel hybrid gels in the system gelatin-GPTMS-TEOS were prepared via a sol-gel route, and their ability to release Si(IV) was examined using MG63 osteoblast-like cell culture. The amount of Si released and the release rate were controllable by changing the mixing ratio of GPTMS and TEOS. In addition, the hybrids had biocompatible surfaces. It is expected that the hybrids will be utilized for the investigation of the effect of Si on cell differentiation and tissue regeneration.
| Original language | English |
|---|---|
| Title of host publication | Bioceramics |
| Editors | Guy Daculsi, Pierre Layrolle |
| Place of Publication | Zurich, Switzerland |
| Publisher | Trans Tech Publications Ltd |
| Pages | 447-450 |
| Number of pages | 4 |
| Volume | 20 |
| ISBN (Print) | 9780878494576, 978-0878494576 |
| Publication status | Published - 30 Mar 2008 |
| Event | 20th International Symposium on Ceramics in Medicine - Nantes, France Duration: 24 Oct 2007 → 26 Oct 2007 |
Publication series
| Name | Key Engineering Materials |
|---|---|
| Publisher | Trans Tech Publications Ltd |
| Volume | 361-363 |
| ISSN (Print) | 1013-9826 |
Conference
| Conference | 20th International Symposium on Ceramics in Medicine |
|---|---|
| Country | France |
| City | Nantes |
| Period | 24/10/07 → 26/10/07 |
Keywords
- cell-material interactions
- tissue engineering
- scaffolds
- organic-inorganic hybrids
- biodegradability
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Cite this
Tsuru, K., Robertson, Z., Annaz, B., & Gibson, I. R. (2008). Sol-Gel Synthesis and in-vitro Cell Compatibility Analysis of Silicate-Containing Biodegradable Hybrid Gels. In G. Daculsi, & P. Layrolle (Eds.), Bioceramics (Vol. 20, pp. 447-450). (Key Engineering Materials; Vol. 361-363). Trans Tech Publications Ltd.