Spatio-temporal population genetics of Biomphalaria pfeifferi in the Zimbabwean Highveld using RAPD markers

J. P. Webster, C. M. Davies, J. Ndamba, Catherine Sue Jones, Leslie Robert Noble, M.E.J. Woolhouse

Research output: Contribution to journalArticle

Abstract

Genetic variation among temporally and spatially defined populations of the schistosome intermediate host, Biomphalaria pfeifferi, was analysed using RAPD markers. Snails were collected from each of eight sites that were 1-20 km apart, on four occasions, over a 2-year period. High levels of genetic variability were found within populations, between populations and between collections. Spatial differentiation and intrapopulation similarity were highest during periods of drought and were lowest following heavy rainfall. Temporal variability, consistent with founder effects, genetic drift and/or differential parasite pressure, was of similar or greater magnitude to that of the spatial variability. The results not only demonstrate that spatio-temporal sampling is necessary to understand the population genetics of short-lived species in variable habitats, but also provide empirical data to support current theoretical models of host-parasite co-evolution.

Original languageEnglish
Pages (from-to)515-527
Number of pages12
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume95
Publication statusPublished - 2001

Keywords

  • SNAIL BULINUS-TRUNCATUS
  • ZIMBABWE HIGHVELD
  • POPULATION-GENETICS
  • NATURAL-POPULATIONS
  • RAPD MARKERS
  • GLOBOSUS
  • COEVOLUTION
  • FERTILIZATION
  • COMPATIBILITY
  • POLYMORPHISM

Cite this

Spatio-temporal population genetics of Biomphalaria pfeifferi in the Zimbabwean Highveld using RAPD markers. / Webster, J. P.; Davies, C. M.; Ndamba, J.; Jones, Catherine Sue; Noble, Leslie Robert; Woolhouse, M.E.J.

In: American Journal of Tropical Medicine and Hygiene, Vol. 95, 2001, p. 515-527.

Research output: Contribution to journalArticle

Webster, J. P. ; Davies, C. M. ; Ndamba, J. ; Jones, Catherine Sue ; Noble, Leslie Robert ; Woolhouse, M.E.J. / Spatio-temporal population genetics of Biomphalaria pfeifferi in the Zimbabwean Highveld using RAPD markers. In: American Journal of Tropical Medicine and Hygiene. 2001 ; Vol. 95. pp. 515-527.
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T1 - Spatio-temporal population genetics of Biomphalaria pfeifferi in the Zimbabwean Highveld using RAPD markers

AU - Webster, J. P.

AU - Davies, C. M.

AU - Ndamba, J.

AU - Jones, Catherine Sue

AU - Noble, Leslie Robert

AU - Woolhouse, M.E.J.

PY - 2001

Y1 - 2001

N2 - Genetic variation among temporally and spatially defined populations of the schistosome intermediate host, Biomphalaria pfeifferi, was analysed using RAPD markers. Snails were collected from each of eight sites that were 1-20 km apart, on four occasions, over a 2-year period. High levels of genetic variability were found within populations, between populations and between collections. Spatial differentiation and intrapopulation similarity were highest during periods of drought and were lowest following heavy rainfall. Temporal variability, consistent with founder effects, genetic drift and/or differential parasite pressure, was of similar or greater magnitude to that of the spatial variability. The results not only demonstrate that spatio-temporal sampling is necessary to understand the population genetics of short-lived species in variable habitats, but also provide empirical data to support current theoretical models of host-parasite co-evolution.

AB - Genetic variation among temporally and spatially defined populations of the schistosome intermediate host, Biomphalaria pfeifferi, was analysed using RAPD markers. Snails were collected from each of eight sites that were 1-20 km apart, on four occasions, over a 2-year period. High levels of genetic variability were found within populations, between populations and between collections. Spatial differentiation and intrapopulation similarity were highest during periods of drought and were lowest following heavy rainfall. Temporal variability, consistent with founder effects, genetic drift and/or differential parasite pressure, was of similar or greater magnitude to that of the spatial variability. The results not only demonstrate that spatio-temporal sampling is necessary to understand the population genetics of short-lived species in variable habitats, but also provide empirical data to support current theoretical models of host-parasite co-evolution.

KW - SNAIL BULINUS-TRUNCATUS

KW - ZIMBABWE HIGHVELD

KW - POPULATION-GENETICS

KW - NATURAL-POPULATIONS

KW - RAPD MARKERS

KW - GLOBOSUS

KW - COEVOLUTION

KW - FERTILIZATION

KW - COMPATIBILITY

KW - POLYMORPHISM

M3 - Article

VL - 95

SP - 515

EP - 527

JO - American Journal of Tropical Medicine and Hygiene

JF - American Journal of Tropical Medicine and Hygiene

SN - 0002-9637

ER -