Species interactions in a parasite community drive infection risk in a wildlife population

Sandra Telfer, Xavier Lambin, Richard Birtles, Pablo Beldomenico, Sarah Burthe, Steve Paterson, Mike Begon

Research output: Contribution to journalArticle

299 Citations (Scopus)

Abstract

Most hosts, including humans, are simultaneously or sequentially infected with several parasites. A key question is whether patterns of coinfection arise because infection by one parasite species affects susceptibility to others or because of inherent differences between hosts. We used time-series data from individual hosts in natural populations to analyze patterns of infection risk for a microparasite community, detecting large positive and negative effects of other infections. Patterns remain once variations in host susceptibility and exposure are accounted for. Indeed, effects are typically of greater magnitude, and explain more variation in infection risk, than the effects associated with host and environmental factors more commonly considered in disease studies. We highlight the danger of mistaken inference when considering parasite species in isolation rather than parasite communities.

Original languageEnglish
Pages (from-to)243-246
Number of pages4
JournalScience
Volume330
Issue number6001
DOIs
Publication statusPublished - 8 Oct 2010

Keywords

  • cowpox
  • host
  • associations
  • coinfection
  • helminth
  • rodents
  • impact

Cite this

Species interactions in a parasite community drive infection risk in a wildlife population. / Telfer, Sandra; Lambin, Xavier; Birtles, Richard; Beldomenico, Pablo; Burthe, Sarah; Paterson, Steve; Begon, Mike.

In: Science, Vol. 330, No. 6001, 08.10.2010, p. 243-246.

Research output: Contribution to journalArticle

Telfer, S, Lambin, X, Birtles, R, Beldomenico, P, Burthe, S, Paterson, S & Begon, M 2010, 'Species interactions in a parasite community drive infection risk in a wildlife population' Science, vol. 330, no. 6001, pp. 243-246. https://doi.org/10.1126/science.1190333
Telfer, Sandra ; Lambin, Xavier ; Birtles, Richard ; Beldomenico, Pablo ; Burthe, Sarah ; Paterson, Steve ; Begon, Mike. / Species interactions in a parasite community drive infection risk in a wildlife population. In: Science. 2010 ; Vol. 330, No. 6001. pp. 243-246.
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