Stage-specific gene expression in lymphatic filarial nematodes

E Devaney, Samuel Allen Moore Martin, F J Thompson

Research output: Contribution to journalLiterature reviewpeer-review

11 Citations (Scopus)

Abstract

Lymphatic filarial nematodes remain a significant cause of morbidity throughout much of the tropics. One approach to the development of rational control methods is an improved understanding of the basic biology of these organisms in relation to the mechanisms used to complete their life cycles. In this article, Eileen Devaney, Sam Martin and Fiona Thompson review new approaches to defining stage-specific molecules in filarial nematodes, and discuss their recent work on the isolation and characterization of stage-regulated cDNAs from Brugia pahangi.

Original languageEnglish
Pages (from-to)418-424
Number of pages7
JournalParasitology Today
Volume12
Issue number11
DOIs
Publication statusPublished - Nov 1996

Keywords

  • reactive surface-antigens
  • heat-shock proteins
  • Brugia-Pahangi
  • messenger-RNA
  • infective larvae
  • differential display
  • Malayi
  • identification
  • parasites
  • microfilariae

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