TY - JOUR
T1 - STROKOG (stroke and cognition consortium)
T2 - An international consortium to examine the epidemiology, diagnosis, and treatment of neurocognitive disorders in relation to cerebrovascular disease
AU - Sachdev, Perminder S.
AU - Lo, Jessica W.
AU - Crawford, John D.
AU - Mellon, Lisa
AU - Hickey, Anna
AU - Williams, David
AU - Bordet, Regis
AU - Mendyk, Anne-Marie
AU - Gele, Patrick
AU - Deplanque, Dominique
AU - Bae, Hee-Joon
AU - Lim, Jae-Sung
AU - Brodtmann, Amy
AU - Werden, Emilio
AU - Cumming, Toby
AU - Kohler, Sebastian
AU - Verhey, Frans R. J.
AU - Dong, Yan-Hong
AU - Tan, Hui Hui
AU - Chen, Christopher
AU - Xin, Xu
AU - Kalaria, Raj N.
AU - Allan, Louise M.
AU - Akinyemi, Rufus O.
AU - Ogunniyi, Adesola
AU - Klimkowicz-Mrowiec, Aleksandra
AU - Dichgans, Martin
AU - Wollenweber, Frank A.
AU - Zietemann, Vera
AU - Hoffmann, Michael
AU - Desmond, David W.
AU - Linden, Thomas
AU - Blomstrand, Christian
AU - Fagerberg, Bjorn
AU - Skoog, Ingmar
AU - Godefroy, Olivier
AU - Barbay, Melanie
AU - Roussel, Martine
AU - Lee, Byung-Chul
AU - Yu, Kyung-Ho
AU - Wardlaw, Joanna
AU - Makin, Stephen J.
AU - Doubal, Fergus N.
AU - Chappell, Francesca M.
AU - Srikanth, Velandai K.
AU - Thrift, Amanda G.
AU - Donnan, Geoffrey A.
AU - Kandiah, Nagaendran
AU - Chander, Russell J.
AU - Lin, Xuling
AU - Cordonnier, Charlotte
AU - Moulin, Solene
AU - Rossi, Costanza
AU - Sabayan, Behnam
AU - Stott, David J.
AU - Jukema, J. Wouter
AU - Melkas, Susanna
AU - Jokinen, Hanna
AU - Erkinjuntti, Timo
AU - Mok, Vincent C. T.
AU - Wong, Adrian
AU - Lam, Bonnie Y. K.
AU - Leys, Didier
AU - Henon, Hilde
AU - Bombois, Stephanie
AU - Lipnicki, Darren M.
AU - Kochan, Nicole A.
N1 - ASPIRE‐S: The authors acknowledge the ASPIRE‐S Steering Group members: Professor Hannah McGee, Royal College of Surgeons in Ireland; Professor Emer Shelley, Royal College of Surgeons in Ireland; Professor Peter Kelly, Mater Misericordiae University Hospital, Dublin; Dr Eamon Dolan, Connolly Hospital, Dublin. BIOSTROKE and STROKDEM: French Health Ministery, the Vascog FHU, the ‘Fondation Coeur et Artères’. CANVAS: CANVAS researchers wish to acknowledge support from the NHMRC (APP1020526 and APP1094974), Sidney and Fiona Myer Foundation and the Collie Trust. CASPER: The CASPER project team consists of Ms. Syenna Schievink, Ms Elles Douven, Dr Sebastian Köhler, Dr Pauline Aalten, Dr Julie Staals, Professor Robert van Oostenbrugge, and Professor Frans Verhey. COAST: The authors thank all participants for their involvement, the research team from NUHS Memory Ageing and Cognition Centre for data collection. CogFAST‐UK: The authors are very grateful to the patients, families, clinical staff and previous co‐investigators for their co‐operation and help with the execution of the study. CogFAST‐Nigeria: The authors are very grateful to the patients, families and clinical staff for their co‐operation and help with the execution of the study. DSDB: The Durban Cerebrovascular Group, Department of Surgery and Neurology, University of Kwa‐Zulu Natal and Entabeni Hospital Stroke Center, Durban, South Africa. GRECOG‐VASC: French Health Ministry. MSS‐II: MMS2 acknowledges the Wellcome Trust, Row Fogo Charitable Trust; Fergus Doubal is supported by the Stroke Association and Garfield Weston Foundation. NEMESIS: The National Health and Medical Research Council of Australia (NHMRC). PITCH: Charlotte Cordonnier is a member of the Institut Universitaire de France.
: R.N.K. was supported
by grants from the Newcastle Centre for Brain Ageing
and Vitality (BBSRC, EPSRC, ESRC and MRC, LLHW;
G0700718). The original CogFAST-UK research programmes were supported by the UK Medical Research
Council (MRC, G0500247 and G9817621). CogFASTNigeria: R.O.A. was supported by a fellowship from the International Brain Research Organization (IBRO) Paris,
France and by an ORS Award from the Newcastle University, UK. DEDEMAS: Vascular Dementia Research Foundation. Flutemetamol (18F) was provided by GE
Healthcare. Epi USA: National Institutes of Health (grants
R01-NS26179 and P01-AG07232). GRECOG-VASC:
French Health Ministry. MSS-II: Wellcome Trust number
WT088134/Z/09/A.Row Fogo Trust.
NHMRC. Grant Numbers: APP1020526, APP1094974
Sidney and Fiona Myer Foundation
Collie Trust
Stroke Association and Garfield Weston Foundation
PY - 2017
Y1 - 2017
N2 - INTRODUCTION: The Stroke and Cognition consortium (STROKOG) aims to facilitate a better understanding of the determinants of vascular contributions to cognitive disorders and help improve the diagnosis and treatment of vascular cognitive disorders (VCD). METHODS: Longitudinal studies with >/=75 participants who had suffered or were at risk of stroke or TIA and which evaluated cognitive function were invited to join STROKOG. The consortium will facilitate projects investigating rates and patterns of cognitive decline, risk factors for VCD, and biomarkers of vascular dementia. RESULTS: Currently, STROKOG includes 25 (21 published) studies, with 12,092 participants from five continents. The duration of follow-up ranges from 3 months to 21 years. DISCUSSION: Although data harmonization will be a key challenge, STROKOG is in a unique position to reuse and combine international cohort data and fully explore patient level characteristics and outcomes. STROKOG could potentially transform our understanding of VCD and have a worldwide impact on promoting better vascular cognitive outcomes.
AB - INTRODUCTION: The Stroke and Cognition consortium (STROKOG) aims to facilitate a better understanding of the determinants of vascular contributions to cognitive disorders and help improve the diagnosis and treatment of vascular cognitive disorders (VCD). METHODS: Longitudinal studies with >/=75 participants who had suffered or were at risk of stroke or TIA and which evaluated cognitive function were invited to join STROKOG. The consortium will facilitate projects investigating rates and patterns of cognitive decline, risk factors for VCD, and biomarkers of vascular dementia. RESULTS: Currently, STROKOG includes 25 (21 published) studies, with 12,092 participants from five continents. The duration of follow-up ranges from 3 months to 21 years. DISCUSSION: Although data harmonization will be a key challenge, STROKOG is in a unique position to reuse and combine international cohort data and fully explore patient level characteristics and outcomes. STROKOG could potentially transform our understanding of VCD and have a worldwide impact on promoting better vascular cognitive outcomes.
KW - Cohort studies
KW - Vascular dementia
KW - Post-stroke dementia
KW - Vascular cognitive disorder
KW - Small vessel disease
KW - Data harmonization
KW - International consortium
UR - https://alz-journals.onlinelibrary.wiley.com/doi/abs/10.1016/j.dadm.2016.10.006
U2 - 10.1016/j.dadm.2016.10.006
DO - 10.1016/j.dadm.2016.10.006
M3 - Article
VL - 7
SP - 11
EP - 23
JO - Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
JF - Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
SN - 2352-8729
ER -