SWATted away: the challenging experience of setting up a programme of SWATs in paediatric trials

Jacqueline Martin-Kerry; Adwoa Parker; Peter Bower; Ian Watt; Shaun Treweek; David Torgerson; Catherine Arundel; Peter Knapp

doi:10.1186/s13063-019-3236-4

SWATted away: the challenging experience of setting up a programme of SWATs in paediatric trials

Jacqueline Martin-Kerry (Corresponding Author), Adwoa Parker, Peter Bower, Ian Watt, Shaun Treweek, David Torgerson, Catherine Arundel, Peter Knapp

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

11 Downloads (Pure)

Abstract

Randomised controlled trials are considered the best method for determining the effectiveness and safety of health interventions. Trials involving children are essential to ensure that treatments are safe and effective. However, many trials, in both adult and paediatric populations, do not achieve recruitment targets and/or maintain retention of participants, which can lead to a reduction in the internal and external validity of the results. Identifying ways of improving trial efficiency are important in order to increase the successful completion of trials.

Original language	English
Article number	141
Journal	Trials
Volume	20
Issue number	1
DOIs	https://doi.org/10.1186/s13063-019-3236-4
Publication status	Published - 19 Feb 2019

Bibliographical note

The authors wish to acknowledge the National Institute of Health Research (NIHR) Health Services and Delivery Research funding for the TRECA study (NIHR Health Services and Delivery Research Project: 14/21/21). The NIHR did not have a role in the design of the study or the writing of this manuscript. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health.

Keywords

‘SStudy Within A Trial’ (SWAT)
embedded trials
methodology
challenges
randomised controlled trials
paediatrics
governance
'SStudy Within A Trial' (SWAT)

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10.1186/s13063-019-3236-4Licence: CC BY

SWATted away: the challenging experience of setting up a programme of SWATs in paediatric trials
© The Author(s). 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated
Final published version, 573 KBLicence: CC BY

Cite this

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SWATted away: the challenging experience of setting up a programme of SWATs in paediatric trials

Abstract

Bibliographical note

Keywords

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