Synthesis and antiviral activity against Coxsackie virus B3 of some novel benzimidazole derivatives

Jun Cheng, Jiangtao Xie, Xianjin Luo

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102 Citations (Scopus)

Abstract

Some benzimidazole derivatives were synthesized and evaluated for their antiviral properties. Compounds 20 and 21 showed potent selective activity against Coxsackie virus B-3 in VERO cells. Some structure-activity relationships were discussed. (C) 2004 Elsevier Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)267-269
Number of pages3
JournalBioorganic & Medicinal Chemistry Letters
Volume15
Issue number2
Early online date24 Nov 2004
DOIs
Publication statusPublished - 17 Jan 2005

Keywords

  • benzimidazole
  • Coxsackie virus B3
  • antiviral

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