Systematic review of sacral nerve stimulation for faecal incontinence and constipation

M. E. D. Jarrett, Graham Mowatt, Cathryn M. A. Glazener, Cynthia M. Fraser, R. J. Nicholls, Adrian M. Grant, M. A. Kamm

Research output: Contribution to journalArticle

219 Citations (Scopus)

Abstract

Background and method: This systematic review assesses the efficacy and safety of sacral nerve stimulation (SNS) for faecal incontinence and constipation. Electronic databases and selected websites were searched for studies evaluating SNS in the treatment of faecal incontinence or constipation. Primary outcome measures included episodes of faecal incontinence per week (faecal incontinence studies) and number of evacuations per week (constipation studies).

Results: From 106 potentially relevant reports, six patient series and one crossover study of SNS for faecal incontinence, and four patient series and one crossover study of SNS for constipation, were included. After implantation, 41 - 75 per cent of patients achieved complete faecal continence and 75 - 100 per cent experienced improvement in episodes of incontinence. There were 19 adverse events among 149 patients. The small crossover study reported increased episodes of faecal incontinence when the implanted pulse generator was switched off. Case series of SNS for constipation reported an increased frequency of evacuation. There were four adverse events among the 20 patients with a permanent implant. The small crossover study reported a reduced number of evacuations when the pulse generator was switched off.

Conclusion: SNS results in significant improvement in faecal incontinence in patients resistant to conservative treatment. Early data also suggest benefit in the treatment of constipation.

Original languageEnglish
Pages (from-to)1559-1569
Number of pages11
JournalBritish Journal of Surgery
Volume91
Issue number12
DOIs
Publication statusPublished - Dec 2004

Keywords

  • severe idiopathic constipation
  • internal anal-sphincter
  • spinal nerve
  • obstetric trauma
  • management
  • transit
  • electrostimulation
  • neuromodulation
  • dysfunction
  • prevalence

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