Systematic review of the literature on the ophthalmological side effects of interferons

Yara Fragoso; Marina Sanchez; sahm Paggiaro; Roberta Mastomauro; Gabriela da Silva Jacondino; Heather M Wilson

doi:10.1590/S0004-27492011000400017

Systematic review of the literature on the ophthalmological side effects of interferons

Yara Fragoso, Marina Sanchez, sahm Paggiaro, Roberta Mastomauro, Gabriela da Silva Jacondino, Heather M Wilson

Applied Medicine

Universidade Metropolitana de Santos

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

Interferons alpha and beta has been used worldwide for a few decades, altering the natural history of several severe diseases including hepatitis C, cancer and immune-mediated conditions such as multiple sclerosis. The adverse events profile of interferons is well established, but only isolated reports of ophthalmological complication of interferon therapy have been published. The objective of this work was to carry out a systematic review of the literature on the subject, bringing to light the need for careful ophthalmological monitoring of patients undergoing interferon treatment.
Nearly 500 cases of ophthalmological complications related to interferon have been reported. The most frequent findings were soft exudates, hemorrhage and ischemia of the retina.

Original language	English
Pages (from-to)	306-310
Number of pages	5
Journal	Arquivos Brasileiros de Oftalmologia
Volume	74
Issue number	4
DOIs	https://doi.org/10.1590/S0004-27492011000400017
Publication status	Published - 2011

Keywords

Eye
Interferon alpha/adverse effects
Interferon beta/adverse effects
Retina

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1590/S0004-27492011000400017

Cite this

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AU - da Silva Jacondino, Gabriela

AU - Wilson, Heather M

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Systematic review of the literature on the ophthalmological side effects of interferons

Abstract

Keywords

UN SDGs

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