Systematic review of the literature on the ophthalmological side effects of interferons

Yara Fragoso; Marina Sanchez; sahm Paggiaro; Roberta Mastomauro; Gabriela da Silva Jacondino; Heather M Wilson

Systematic review of the literature on the ophthalmological side effects of interferons

Yara Fragoso, Marina Sanchez, sahm Paggiaro, Roberta Mastomauro, Gabriela da Silva Jacondino, Heather M Wilson

Research output: Contribution to journal › Article › peer-review

Abstract

Interferons alpha and beta has been used worldwide for a few decades, altering the natural history of several severe diseases including hepatitis C, cancer and immune-mediated conditions such as multiple sclerosis. The adverse events profile of interferons is well established, but only isolated reports of ophthalmological complication of interferon therapy have been published. The objective of this work was to carry out a systematic review of the literature on the subject, bringing to light the need for careful ophthalmological monitoring of patients undergoing interferon treatment.
Nearly 500 cases of ophthalmological complications related to interferon have been reported. The most frequent findings were soft exudates, hemorrhage and ischemia of the retina.

Original language	English
Journal	Arquivos Brasileiros de Oftalmologia
Publication status	Accepted/In press - 2011

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title = "Systematic review of the literature on the ophthalmological side effects of interferons",

abstract = "Interferons alpha and beta has been used worldwide for a few decades, altering the natural history of several severe diseases including hepatitis C, cancer and immune-mediated conditions such as multiple sclerosis. The adverse events profile of interferons is well established, but only isolated reports of ophthalmological complication of interferon therapy have been published. The objective of this work was to carry out a systematic review of the literature on the subject, bringing to light the need for careful ophthalmological monitoring of patients undergoing interferon treatment. Nearly 500 cases of ophthalmological complications related to interferon have been reported. The most frequent findings were soft exudates, hemorrhage and ischemia of the retina. ",

author = "Yara Fragoso and Marina Sanchez and sahm Paggiaro and Roberta Mastomauro and {da Silva Jacondino}, Gabriela and Wilson, {Heather M}",

year = "2011",

language = "English",

journal = "Arquivos Brasileiros de Oftalmologia",

issn = "0004-2749",

publisher = "Conselho Brasileiro De Oftalmologia",

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TY - JOUR

T1 - Systematic review of the literature on the ophthalmological side effects of interferons

AU - Fragoso, Yara

AU - Sanchez, Marina

AU - Paggiaro, sahm

AU - Mastomauro, Roberta

AU - da Silva Jacondino, Gabriela

AU - Wilson, Heather M

PY - 2011

Y1 - 2011

N2 - Interferons alpha and beta has been used worldwide for a few decades, altering the natural history of several severe diseases including hepatitis C, cancer and immune-mediated conditions such as multiple sclerosis. The adverse events profile of interferons is well established, but only isolated reports of ophthalmological complication of interferon therapy have been published. The objective of this work was to carry out a systematic review of the literature on the subject, bringing to light the need for careful ophthalmological monitoring of patients undergoing interferon treatment. Nearly 500 cases of ophthalmological complications related to interferon have been reported. The most frequent findings were soft exudates, hemorrhage and ischemia of the retina.

AB - Interferons alpha and beta has been used worldwide for a few decades, altering the natural history of several severe diseases including hepatitis C, cancer and immune-mediated conditions such as multiple sclerosis. The adverse events profile of interferons is well established, but only isolated reports of ophthalmological complication of interferon therapy have been published. The objective of this work was to carry out a systematic review of the literature on the subject, bringing to light the need for careful ophthalmological monitoring of patients undergoing interferon treatment. Nearly 500 cases of ophthalmological complications related to interferon have been reported. The most frequent findings were soft exudates, hemorrhage and ischemia of the retina.

M3 - Article

JO - Arquivos Brasileiros de Oftalmologia

JF - Arquivos Brasileiros de Oftalmologia

SN - 0004-2749

ER -

Systematic review of the literature on the ophthalmological side effects of interferons

Abstract

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