Tackling human fungal infections

Gordon D Brown, David W Denning, Stuart M Levitz

Research output: Contribution to journalArticle

282 Citations (Scopus)

Abstract

Fungi infect billions of people every year, yet their contribution to the global burden of disease is largely unrecognized. Most are “relatively” minor infections, but millions contract diseases that kill at least as many people as tuberculosis or malaria. Although true mortality rates are unknown because of a lack of good epidemiological data, the incidence of invasive fungal infections is rising as a result of modern medical interventions and immunosuppressive diseases, such as AIDS. Despite the high mortality rates of invasive fungal infections, they remain understudied and underdiagnosed as compared with other infectious diseases. What can be done to remedy this unfortunate situation?
Original languageEnglish
Pages (from-to)647
JournalScience
Volume336
Issue number6082
DOIs
Publication statusPublished - 11 May 2012

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Keywords

  • Antifungal Agents
  • Biomedical Research
  • Financing, Government
  • Fungal Vaccines
  • Humans
  • Mycoses
  • Research Support as Topic

Cite this

Brown, G. D., Denning, D. W., & Levitz, S. M. (2012). Tackling human fungal infections. Science, 336(6082), 647. https://doi.org/10.1126/science.1222236