Targeting androgen receptor activation function-1 with EPI to overcome resistance mechanisms in castration-resistant prostate cancer

Yu Chi Yang, Carmen Adriana Banuelos, Nasrin R Mawji, Jun Wang, Minoru Kato, Simon Haile, Iain J McEwan, Stephen Plymate, Marianne D Sadar

Research output: Contribution to journalArticle

22 Citations (Scopus)
3 Downloads (Pure)
Original languageEnglish
Pages (from-to)4466–4477
Number of pages12
JournalClinical Cancer Research
Volume22
Issue number17
Early online date2 May 2016
DOIs
Publication statusPublished - 1 Sep 2016

Keywords

  • androgen receptor
  • N-terminal domain
  • EPI
  • castration-resistant prostate cancer
  • resistance mechanisms

Cite this

Targeting androgen receptor activation function-1 with EPI to overcome resistance mechanisms in castration-resistant prostate cancer. / Yang, Yu Chi; Banuelos, Carmen Adriana; Mawji, Nasrin R; Wang, Jun; Kato, Minoru; Haile, Simon; McEwan, Iain J; Plymate, Stephen; Sadar, Marianne D.

In: Clinical Cancer Research, Vol. 22, No. 17, 01.09.2016, p. 4466–4477.

Research output: Contribution to journalArticle

Yang, Yu Chi ; Banuelos, Carmen Adriana ; Mawji, Nasrin R ; Wang, Jun ; Kato, Minoru ; Haile, Simon ; McEwan, Iain J ; Plymate, Stephen ; Sadar, Marianne D. / Targeting androgen receptor activation function-1 with EPI to overcome resistance mechanisms in castration-resistant prostate cancer. In: Clinical Cancer Research. 2016 ; Vol. 22, No. 17. pp. 4466–4477.
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author = "Yang, {Yu Chi} and Banuelos, {Carmen Adriana} and Mawji, {Nasrin R} and Jun Wang and Minoru Kato and Simon Haile and McEwan, {Iain J} and Stephen Plymate and Sadar, {Marianne D}",
note = "Acknowledgments The authors thank Kate Watt (University of Aberdeen, Aberdeen, Scotland) for technical support. The authors are also grateful to Country Meadows Senior Men's Golf Charity Classic for financial support of this research. Financial support: This research was supported by grants to MDS from the NCI (2R01CA105304), the Canadian Institutes of Health Research (MOP79308) and the US Army Medical Research and Materiel Command Prostate Cancer Research Program (E81XWH-11-1-0551). Research by IJM’s group was supported by the Chief Scientist’s Office of the Scottish Government (ETM-258 and -382). We are grateful to Country Meadows Senior Men’s Golf Charity Classic for financial support of this research.",
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AU - Yang, Yu Chi

AU - Banuelos, Carmen Adriana

AU - Mawji, Nasrin R

AU - Wang, Jun

AU - Kato, Minoru

AU - Haile, Simon

AU - McEwan, Iain J

AU - Plymate, Stephen

AU - Sadar, Marianne D

N1 - Acknowledgments The authors thank Kate Watt (University of Aberdeen, Aberdeen, Scotland) for technical support. The authors are also grateful to Country Meadows Senior Men's Golf Charity Classic for financial support of this research. Financial support: This research was supported by grants to MDS from the NCI (2R01CA105304), the Canadian Institutes of Health Research (MOP79308) and the US Army Medical Research and Materiel Command Prostate Cancer Research Program (E81XWH-11-1-0551). Research by IJM’s group was supported by the Chief Scientist’s Office of the Scottish Government (ETM-258 and -382). We are grateful to Country Meadows Senior Men’s Golf Charity Classic for financial support of this research.

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KW - castration-resistant prostate cancer

KW - resistance mechanisms

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