Temporal variation in an immune response gene (MHC I) in anadromous Salmo trutta in an Irish river before and during aquaculture activities

J. Coughlan, P. Mcginnity, B. O'Farrell, E. Dillane, O. Diserud, E. De Eyto, K. Farrell, K. Whelan, Rene Josephus Maria Stet, T. F. Cross

    Research output: Contribution to journalArticle

    22 Citations (Scopus)

    Abstract

    Several studies have documented the genetic effects of intraspecific hybridization of cultured and wild Atlantic salmon (Salmo salar L.). However, the effect of salmon aquaculture on wild congeners is not so well understood. Diseases, introduced or increased in incidence by salmon aquaculture activities, may have an impact on co-occurring wild sea trout (Salmo trutta L.), as implied by the steep decline in sea trout numbers in many Irish, Scottish, and Norwegian rivers since the late 1980s, which may be linked to sea lice infestations associated with marine salmonid farming. Our data suggest that salmon farming and ocean ranching can indirectly affect, most likely mediated by disease, the genetics of cohabiting sea trout by reducing variability at major histocompatibility class I genes. We studied samples of DNA extracted from scales of sea trout in the Burrishoole River, in the west of Ireland, before and at intervals during aquaculture activities. In these samples, allelic variation at a microsatellite marker, tightly linked to a locus critical to immune response (Satr-UBA), was compared with variation at six neutral microsatellite loci. A significant decline in allefic richness and gene diversity at the Satr-UBA marker locus, observed since aquaculture started and which may indicate a selective response, was not reflected by similar reductions at neutral loci. Subsequent recovery of variability at the Satr-UBA marker, seen among later samples, may reflect an increased contribution by resident brown trout to the remaining sea trout stock. (c) 2006 International Council for the Exploration of the Sea. Published by Elsevier Ltd. All rights reserved.

    Original languageEnglish
    Pages (from-to)1248-1255
    Number of pages7
    JournalICES Journal of Marine Science
    Volume63
    DOIs
    Publication statusPublished - 2006

    Keywords

    • MHC
    • microsatellites
    • Salmo trutta
    • sea trout
    • temporal variation
    • HISTOCOMPATIBILITY CLASS-I
    • FRESH-WATER RESIDENT
    • ATLANTIC SALMON
    • BROWN TROUT
    • SALAR L.
    • POPULATION-STRUCTURE
    • MICROSATELLITES
    • LOCUS
    • WILD
    • POLYMORPHISM

    Cite this

    Temporal variation in an immune response gene (MHC I) in anadromous Salmo trutta in an Irish river before and during aquaculture activities. / Coughlan, J.; Mcginnity, P.; O'Farrell, B.; Dillane, E.; Diserud, O.; De Eyto, E.; Farrell, K.; Whelan, K.; Stet, Rene Josephus Maria; Cross, T. F.

    In: ICES Journal of Marine Science, Vol. 63, 2006, p. 1248-1255.

    Research output: Contribution to journalArticle

    Coughlan, J, Mcginnity, P, O'Farrell, B, Dillane, E, Diserud, O, De Eyto, E, Farrell, K, Whelan, K, Stet, RJM & Cross, TF 2006, 'Temporal variation in an immune response gene (MHC I) in anadromous Salmo trutta in an Irish river before and during aquaculture activities', ICES Journal of Marine Science, vol. 63, pp. 1248-1255. https://doi.org/10.1016/j.icesjms.2006.03.025
    Coughlan, J. ; Mcginnity, P. ; O'Farrell, B. ; Dillane, E. ; Diserud, O. ; De Eyto, E. ; Farrell, K. ; Whelan, K. ; Stet, Rene Josephus Maria ; Cross, T. F. / Temporal variation in an immune response gene (MHC I) in anadromous Salmo trutta in an Irish river before and during aquaculture activities. In: ICES Journal of Marine Science. 2006 ; Vol. 63. pp. 1248-1255.
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    abstract = "Several studies have documented the genetic effects of intraspecific hybridization of cultured and wild Atlantic salmon (Salmo salar L.). However, the effect of salmon aquaculture on wild congeners is not so well understood. Diseases, introduced or increased in incidence by salmon aquaculture activities, may have an impact on co-occurring wild sea trout (Salmo trutta L.), as implied by the steep decline in sea trout numbers in many Irish, Scottish, and Norwegian rivers since the late 1980s, which may be linked to sea lice infestations associated with marine salmonid farming. Our data suggest that salmon farming and ocean ranching can indirectly affect, most likely mediated by disease, the genetics of cohabiting sea trout by reducing variability at major histocompatibility class I genes. We studied samples of DNA extracted from scales of sea trout in the Burrishoole River, in the west of Ireland, before and at intervals during aquaculture activities. In these samples, allelic variation at a microsatellite marker, tightly linked to a locus critical to immune response (Satr-UBA), was compared with variation at six neutral microsatellite loci. A significant decline in allefic richness and gene diversity at the Satr-UBA marker locus, observed since aquaculture started and which may indicate a selective response, was not reflected by similar reductions at neutral loci. Subsequent recovery of variability at the Satr-UBA marker, seen among later samples, may reflect an increased contribution by resident brown trout to the remaining sea trout stock. (c) 2006 International Council for the Exploration of the Sea. Published by Elsevier Ltd. All rights reserved.",
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    author = "J. Coughlan and P. Mcginnity and B. O'Farrell and E. Dillane and O. Diserud and {De Eyto}, E. and K. Farrell and K. Whelan and Stet, {Rene Josephus Maria} and Cross, {T. F.}",
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    T1 - Temporal variation in an immune response gene (MHC I) in anadromous Salmo trutta in an Irish river before and during aquaculture activities

    AU - Coughlan, J.

    AU - Mcginnity, P.

    AU - O'Farrell, B.

    AU - Dillane, E.

    AU - Diserud, O.

    AU - De Eyto, E.

    AU - Farrell, K.

    AU - Whelan, K.

    AU - Stet, Rene Josephus Maria

    AU - Cross, T. F.

    PY - 2006

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    N2 - Several studies have documented the genetic effects of intraspecific hybridization of cultured and wild Atlantic salmon (Salmo salar L.). However, the effect of salmon aquaculture on wild congeners is not so well understood. Diseases, introduced or increased in incidence by salmon aquaculture activities, may have an impact on co-occurring wild sea trout (Salmo trutta L.), as implied by the steep decline in sea trout numbers in many Irish, Scottish, and Norwegian rivers since the late 1980s, which may be linked to sea lice infestations associated with marine salmonid farming. Our data suggest that salmon farming and ocean ranching can indirectly affect, most likely mediated by disease, the genetics of cohabiting sea trout by reducing variability at major histocompatibility class I genes. We studied samples of DNA extracted from scales of sea trout in the Burrishoole River, in the west of Ireland, before and at intervals during aquaculture activities. In these samples, allelic variation at a microsatellite marker, tightly linked to a locus critical to immune response (Satr-UBA), was compared with variation at six neutral microsatellite loci. A significant decline in allefic richness and gene diversity at the Satr-UBA marker locus, observed since aquaculture started and which may indicate a selective response, was not reflected by similar reductions at neutral loci. Subsequent recovery of variability at the Satr-UBA marker, seen among later samples, may reflect an increased contribution by resident brown trout to the remaining sea trout stock. (c) 2006 International Council for the Exploration of the Sea. Published by Elsevier Ltd. All rights reserved.

    AB - Several studies have documented the genetic effects of intraspecific hybridization of cultured and wild Atlantic salmon (Salmo salar L.). However, the effect of salmon aquaculture on wild congeners is not so well understood. Diseases, introduced or increased in incidence by salmon aquaculture activities, may have an impact on co-occurring wild sea trout (Salmo trutta L.), as implied by the steep decline in sea trout numbers in many Irish, Scottish, and Norwegian rivers since the late 1980s, which may be linked to sea lice infestations associated with marine salmonid farming. Our data suggest that salmon farming and ocean ranching can indirectly affect, most likely mediated by disease, the genetics of cohabiting sea trout by reducing variability at major histocompatibility class I genes. We studied samples of DNA extracted from scales of sea trout in the Burrishoole River, in the west of Ireland, before and at intervals during aquaculture activities. In these samples, allelic variation at a microsatellite marker, tightly linked to a locus critical to immune response (Satr-UBA), was compared with variation at six neutral microsatellite loci. A significant decline in allefic richness and gene diversity at the Satr-UBA marker locus, observed since aquaculture started and which may indicate a selective response, was not reflected by similar reductions at neutral loci. Subsequent recovery of variability at the Satr-UBA marker, seen among later samples, may reflect an increased contribution by resident brown trout to the remaining sea trout stock. (c) 2006 International Council for the Exploration of the Sea. Published by Elsevier Ltd. All rights reserved.

    KW - MHC

    KW - microsatellites

    KW - Salmo trutta

    KW - sea trout

    KW - temporal variation

    KW - HISTOCOMPATIBILITY CLASS-I

    KW - FRESH-WATER RESIDENT

    KW - ATLANTIC SALMON

    KW - BROWN TROUT

    KW - SALAR L.

    KW - POPULATION-STRUCTURE

    KW - MICROSATELLITES

    KW - LOCUS

    KW - WILD

    KW - POLYMORPHISM

    U2 - 10.1016/j.icesjms.2006.03.025

    DO - 10.1016/j.icesjms.2006.03.025

    M3 - Article

    VL - 63

    SP - 1248

    EP - 1255

    JO - ICES Journal of Marine Science

    JF - ICES Journal of Marine Science

    SN - 1054-3139

    ER -