The Authors Reply: Reply to 'Is the Heart Really Stressed Out of Energy?'

Dana K Dawson; Christopher J Neil; Anke Henning; Donnie Cameron; Baljit Jagpal; Margaret Bruce; John Horowitz; Michael P Frenneaux

doi:10.1016/j.jcmg.2015.03.015

The Authors Reply: Reply to 'Is the Heart Really Stressed Out of Energy?'

Dana K Dawson, Christopher J Neil, Anke Henning, Donnie Cameron, Baljit Jagpal, Margaret Bruce, John Horowitz, Michael P Frenneaux

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Refers To
Zhongxia Sun, Pahul Singh, Tiemin Wei, Hani Kozman, Kan Liu
Is the Heart Really Stressed Out of Energy? JACC: Cardiovascular Imaging, Volume 9, Issue 5, May 2016, Pages 633-635

We thank Dr. Sun and colleagues for their interest in our publication (1) and for their questions that highlight important pathophysiological phenomena that appear unique to Tako-tsubo cardiomyopathy (TTC).

It is true that for the same extent of left ventricular (LV) systolic impairment and indeed for the same degree of elevation of LV end-diastolic pressure (2), patients appear to have lesser degrees of pulmonary edema in acute TTC compared with those experiencing a large acute myocardial infarction (AMI). However, this does not mean that the clinical course in the early stages of acute TTC is “benign.” Conversely, there are significant hemodynamic, arrhythmic, and embolic complications, all of which are life threatening and place the early in-hospital mortality of acute TTC on par with that of AMI

Original language	English
Pages (from-to)	635-636
Number of pages	2
Journal	JACC. Cardiovascular Imaging
Volume	9
Issue number	5
Early online date	17 Feb 2016
DOIs	https://doi.org/10.1016/j.jcmg.2015.03.015
Publication status	Published - May 2016

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title = "The Authors Reply: Reply to 'Is the Heart Really Stressed Out of Energy?'",

abstract = "Refers ToZhongxia Sun, Pahul Singh, Tiemin Wei, Hani Kozman, Kan LiuIs the Heart Really Stressed Out of Energy? JACC: Cardiovascular Imaging, Volume 9, Issue 5, May 2016, Pages 633-635We thank Dr. Sun and colleagues for their interest in our publication (1) and for their questions that highlight important pathophysiological phenomena that appear unique to Tako-tsubo cardiomyopathy (TTC).It is true that for the same extent of left ventricular (LV) systolic impairment and indeed for the same degree of elevation of LV end-diastolic pressure (2), patients appear to have lesser degrees of pulmonary edema in acute TTC compared with those experiencing a large acute myocardial infarction (AMI). However, this does not mean that the clinical course in the early stages of acute TTC is “benign.” Conversely, there are significant hemodynamic, arrhythmic, and embolic complications, all of which are life threatening and place the early in-hospital mortality of acute TTC on par with that of AMI",

author = "Dawson, {Dana K} and Neil, {Christopher J} and Anke Henning and Donnie Cameron and Baljit Jagpal and Margaret Bruce and John Horowitz and Frenneaux, {Michael P}",

year = "2016",

month = may,

doi = "10.1016/j.jcmg.2015.03.015",

language = "English",

volume = "9",

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T2 - Reply to 'Is the Heart Really Stressed Out of Energy?'

AU - Dawson, Dana K

AU - Neil, Christopher J

AU - Henning, Anke

AU - Cameron, Donnie

AU - Jagpal, Baljit

AU - Bruce, Margaret

AU - Horowitz, John

AU - Frenneaux, Michael P

PY - 2016/5

Y1 - 2016/5

N2 - Refers ToZhongxia Sun, Pahul Singh, Tiemin Wei, Hani Kozman, Kan LiuIs the Heart Really Stressed Out of Energy? JACC: Cardiovascular Imaging, Volume 9, Issue 5, May 2016, Pages 633-635We thank Dr. Sun and colleagues for their interest in our publication (1) and for their questions that highlight important pathophysiological phenomena that appear unique to Tako-tsubo cardiomyopathy (TTC).It is true that for the same extent of left ventricular (LV) systolic impairment and indeed for the same degree of elevation of LV end-diastolic pressure (2), patients appear to have lesser degrees of pulmonary edema in acute TTC compared with those experiencing a large acute myocardial infarction (AMI). However, this does not mean that the clinical course in the early stages of acute TTC is “benign.” Conversely, there are significant hemodynamic, arrhythmic, and embolic complications, all of which are life threatening and place the early in-hospital mortality of acute TTC on par with that of AMI

AB - Refers ToZhongxia Sun, Pahul Singh, Tiemin Wei, Hani Kozman, Kan LiuIs the Heart Really Stressed Out of Energy? JACC: Cardiovascular Imaging, Volume 9, Issue 5, May 2016, Pages 633-635We thank Dr. Sun and colleagues for their interest in our publication (1) and for their questions that highlight important pathophysiological phenomena that appear unique to Tako-tsubo cardiomyopathy (TTC).It is true that for the same extent of left ventricular (LV) systolic impairment and indeed for the same degree of elevation of LV end-diastolic pressure (2), patients appear to have lesser degrees of pulmonary edema in acute TTC compared with those experiencing a large acute myocardial infarction (AMI). However, this does not mean that the clinical course in the early stages of acute TTC is “benign.” Conversely, there are significant hemodynamic, arrhythmic, and embolic complications, all of which are life threatening and place the early in-hospital mortality of acute TTC on par with that of AMI

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DO - 10.1016/j.jcmg.2015.03.015

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SN - 1936-878X

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SP - 635

EP - 636

JO - JACC. Cardiovascular Imaging

JF - JACC. Cardiovascular Imaging

IS - 5

ER -

The Authors Reply: Reply to 'Is the Heart Really Stressed Out of Energy?'

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