The Authors Reply

Reply to 'Is the Heart Really Stressed Out of Energy?'

Dana K Dawson, Christopher J Neil, Anke Henning, Donnie Cameron, Baljit Jagpal, Margaret Bruce, John Horowitz, Michael P Frenneaux

Research output: Contribution to journalComment/debate

Abstract

Refers To
Zhongxia Sun, Pahul Singh, Tiemin Wei, Hani Kozman, Kan Liu
Is the Heart Really Stressed Out of Energy? JACC: Cardiovascular Imaging, Volume 9, Issue 5, May 2016, Pages 633-635

We thank Dr. Sun and colleagues for their interest in our publication (1) and for their questions that highlight important pathophysiological phenomena that appear unique to Tako-tsubo cardiomyopathy (TTC).

It is true that for the same extent of left ventricular (LV) systolic impairment and indeed for the same degree of elevation of LV end-diastolic pressure (2), patients appear to have lesser degrees of pulmonary edema in acute TTC compared with those experiencing a large acute myocardial infarction (AMI). However, this does not mean that the clinical course in the early stages of acute TTC is “benign.” Conversely, there are significant hemodynamic, arrhythmic, and embolic complications, all of which are life threatening and place the early in-hospital mortality of acute TTC on par with that of AMI
Original languageEnglish
Pages (from-to)635-636
Number of pages2
JournalJACC. Cardiovascular Imaging
Volume9
Issue number5
Early online date17 Feb 2016
DOIs
Publication statusPublished - May 2016

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Takotsubo Cardiomyopathy
Solar System
Myocardial Infarction
Pulmonary Edema
Hospital Mortality
Hemodynamics
Blood Pressure

Cite this

Dawson, D. K., Neil, C. J., Henning, A., Cameron, D., Jagpal, B., Bruce, M., ... Frenneaux, M. P. (2016). The Authors Reply: Reply to 'Is the Heart Really Stressed Out of Energy?'. JACC. Cardiovascular Imaging, 9(5), 635-636. https://doi.org/10.1016/j.jcmg.2015.03.015

The Authors Reply : Reply to 'Is the Heart Really Stressed Out of Energy?'. / Dawson, Dana K; Neil, Christopher J; Henning, Anke; Cameron, Donnie; Jagpal, Baljit; Bruce, Margaret; Horowitz, John; Frenneaux, Michael P.

In: JACC. Cardiovascular Imaging, Vol. 9, No. 5, 05.2016, p. 635-636.

Research output: Contribution to journalComment/debate

Dawson, DK, Neil, CJ, Henning, A, Cameron, D, Jagpal, B, Bruce, M, Horowitz, J & Frenneaux, MP 2016, 'The Authors Reply: Reply to 'Is the Heart Really Stressed Out of Energy?'', JACC. Cardiovascular Imaging, vol. 9, no. 5, pp. 635-636. https://doi.org/10.1016/j.jcmg.2015.03.015
Dawson, Dana K ; Neil, Christopher J ; Henning, Anke ; Cameron, Donnie ; Jagpal, Baljit ; Bruce, Margaret ; Horowitz, John ; Frenneaux, Michael P. / The Authors Reply : Reply to 'Is the Heart Really Stressed Out of Energy?'. In: JACC. Cardiovascular Imaging. 2016 ; Vol. 9, No. 5. pp. 635-636.
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AU - Horowitz, John

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AB - Refers ToZhongxia Sun, Pahul Singh, Tiemin Wei, Hani Kozman, Kan LiuIs the Heart Really Stressed Out of Energy? JACC: Cardiovascular Imaging, Volume 9, Issue 5, May 2016, Pages 633-635We thank Dr. Sun and colleagues for their interest in our publication (1) and for their questions that highlight important pathophysiological phenomena that appear unique to Tako-tsubo cardiomyopathy (TTC).It is true that for the same extent of left ventricular (LV) systolic impairment and indeed for the same degree of elevation of LV end-diastolic pressure (2), patients appear to have lesser degrees of pulmonary edema in acute TTC compared with those experiencing a large acute myocardial infarction (AMI). However, this does not mean that the clinical course in the early stages of acute TTC is “benign.” Conversely, there are significant hemodynamic, arrhythmic, and embolic complications, all of which are life threatening and place the early in-hospital mortality of acute TTC on par with that of AMI

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