The Butyrivibrio fibrisolvens tet(W) gene is carried on the novel conjugative transposon TnB1230, which contains duplicated nitroreductase coding sequences

C M Melville, R Brunel, Harry James Flint, Karen Patricia Scott

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

The Butyrivibrio fibrisolvens tet(W) gene is located on the conjugative transposon TnB1230. TnB1230 encodes transfer proteins with 48 to 67% identity to some of those encoded by Tn1549. tet(W) is flanked by directly repeated sequences with significant homology to oxygen-insensitive nitroreductases. The 340 nucleotides upstream of tet(W) are strongly conserved and are required for tetracycline resistance.

Original languageEnglish
Pages (from-to)3656-3659
Number of pages4
JournalJournal of Bacteriology
Volume186
Issue number11
DOIs
Publication statusPublished - Jun 2004

Keywords

  • tetracycline resistance genes
  • DNA-sequences
  • human gut
  • bacteria
  • transcription
  • determinants
  • expression
  • mechanisms
  • element
  • rumen

Cite this

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title = "The Butyrivibrio fibrisolvens tet(W) gene is carried on the novel conjugative transposon TnB1230, which contains duplicated nitroreductase coding sequences",
abstract = "The Butyrivibrio fibrisolvens tet(W) gene is located on the conjugative transposon TnB1230. TnB1230 encodes transfer proteins with 48 to 67{\%} identity to some of those encoded by Tn1549. tet(W) is flanked by directly repeated sequences with significant homology to oxygen-insensitive nitroreductases. The 340 nucleotides upstream of tet(W) are strongly conserved and are required for tetracycline resistance.",
keywords = "tetracycline resistance genes, DNA-sequences, human gut, bacteria, transcription, determinants, expression, mechanisms, element, rumen",
author = "Melville, {C M} and R Brunel and Flint, {Harry James} and Scott, {Karen Patricia}",
year = "2004",
month = "6",
doi = "10.1128/JB.186.11.3656-3659.2004",
language = "English",
volume = "186",
pages = "3656--3659",
journal = "Journal of Bacteriology",
issn = "0021-9193",
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T1 - The Butyrivibrio fibrisolvens tet(W) gene is carried on the novel conjugative transposon TnB1230, which contains duplicated nitroreductase coding sequences

AU - Melville, C M

AU - Brunel, R

AU - Flint, Harry James

AU - Scott, Karen Patricia

PY - 2004/6

Y1 - 2004/6

N2 - The Butyrivibrio fibrisolvens tet(W) gene is located on the conjugative transposon TnB1230. TnB1230 encodes transfer proteins with 48 to 67% identity to some of those encoded by Tn1549. tet(W) is flanked by directly repeated sequences with significant homology to oxygen-insensitive nitroreductases. The 340 nucleotides upstream of tet(W) are strongly conserved and are required for tetracycline resistance.

AB - The Butyrivibrio fibrisolvens tet(W) gene is located on the conjugative transposon TnB1230. TnB1230 encodes transfer proteins with 48 to 67% identity to some of those encoded by Tn1549. tet(W) is flanked by directly repeated sequences with significant homology to oxygen-insensitive nitroreductases. The 340 nucleotides upstream of tet(W) are strongly conserved and are required for tetracycline resistance.

KW - tetracycline resistance genes

KW - DNA-sequences

KW - human gut

KW - bacteria

KW - transcription

KW - determinants

KW - expression

KW - mechanisms

KW - element

KW - rumen

U2 - 10.1128/JB.186.11.3656-3659.2004

DO - 10.1128/JB.186.11.3656-3659.2004

M3 - Article

VL - 186

SP - 3656

EP - 3659

JO - Journal of Bacteriology

JF - Journal of Bacteriology

SN - 0021-9193

IS - 11

ER -