The Butyrivibrio fibrisolvens tet(W) gene is carried on the novel conjugative transposon TnB1230, which contains duplicated nitroreductase coding sequences

C M  Melville; R  Brunel; Harry James Flint; Karen Patricia Scott

doi:10.1128/JB.186.11.3656-3659.2004

The Butyrivibrio fibrisolvens tet(W) gene is carried on the novel conjugative transposon TnB1230, which contains duplicated nitroreductase coding sequences

C M Melville, R Brunel, Harry James Flint, Karen Patricia Scott

The Rowett Institute of Nutrition and Health

Research output: Contribution to journal › Article › peer-review

40 Citations (Scopus)

Abstract

The Butyrivibrio fibrisolvens tet(W) gene is located on the conjugative transposon TnB1230. TnB1230 encodes transfer proteins with 48 to 67% identity to some of those encoded by Tn1549. tet(W) is flanked by directly repeated sequences with significant homology to oxygen-insensitive nitroreductases. The 340 nucleotides upstream of tet(W) are strongly conserved and are required for tetracycline resistance.

Original language	English
Pages (from-to)	3656-3659
Number of pages	4
Journal	Journal of Bacteriology
Volume	186
Issue number	11
DOIs	https://doi.org/10.1128/JB.186.11.3656-3659.2004
Publication status	Published - Jun 2004

Keywords

tetracycline resistance genes
DNA-sequences
human gut
bacteria
transcription
determinants
expression
mechanisms
element
rumen

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10.1128/JB.186.11.3656-3659.2004

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title = "The Butyrivibrio fibrisolvens tet(W) gene is carried on the novel conjugative transposon TnB1230, which contains duplicated nitroreductase coding sequences",

abstract = "The Butyrivibrio fibrisolvens tet(W) gene is located on the conjugative transposon TnB1230. TnB1230 encodes transfer proteins with 48 to 67% identity to some of those encoded by Tn1549. tet(W) is flanked by directly repeated sequences with significant homology to oxygen-insensitive nitroreductases. The 340 nucleotides upstream of tet(W) are strongly conserved and are required for tetracycline resistance.",

keywords = "tetracycline resistance genes, DNA-sequences, human gut, bacteria, transcription, determinants, expression, mechanisms, element, rumen",

author = "Melville, {C M} and R Brunel and Flint, {Harry James} and Scott, {Karen Patricia}",

year = "2004",

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doi = "10.1128/JB.186.11.3656-3659.2004",

language = "English",

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AU - Melville, C M

AU - Brunel, R

AU - Flint, Harry James

AU - Scott, Karen Patricia

PY - 2004/6

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AB - The Butyrivibrio fibrisolvens tet(W) gene is located on the conjugative transposon TnB1230. TnB1230 encodes transfer proteins with 48 to 67% identity to some of those encoded by Tn1549. tet(W) is flanked by directly repeated sequences with significant homology to oxygen-insensitive nitroreductases. The 340 nucleotides upstream of tet(W) are strongly conserved and are required for tetracycline resistance.

KW - tetracycline resistance genes

KW - DNA-sequences

KW - human gut

KW - bacteria

KW - transcription

KW - determinants

KW - expression

KW - mechanisms

KW - element

KW - rumen

U2 - 10.1128/JB.186.11.3656-3659.2004

DO - 10.1128/JB.186.11.3656-3659.2004

M3 - Article

SN - 0021-9193

VL - 186

SP - 3656

EP - 3659

JO - Journal of Bacteriology

JF - Journal of Bacteriology

IS - 11

ER -

The Butyrivibrio fibrisolvens tet(W) gene is carried on the novel conjugative transposon TnB1230, which contains duplicated nitroreductase coding sequences

Abstract

Keywords

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