The CARES-SF used for prospective assessment of health related quality of life after stem cell transplantation

M. J. Hjermstad, S. A. Evensen, S. O. kvaloy, J. H. Loge, Peter Fayers, S. Kaasa

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Objective: By employing the Cancer Rehabilitation and Evaluation System short form (CARES-SF) prospectively we wanted to focus on the rehabilitation needs after high-dose chemotherapy (HDC) and stem cell transplantation, in order to identify problems that should be addressed by health-care professionals during the course of disease and treatment.

Methods: The CARES-SF was administered before and at 2, 6 and 12 months post-transplant to 130 cancer patients treated with HDC and allogeneic (SCT) or autologous stem cell transplantation (ASCT). Physical function scale scores were compared with the corresponding scale of the EORTC QLQ-C30.

Results: The SCT group reported significantly better physical function than the ASCT group before transplant on both the CARES-SF (p<0.0001) and the EORTC QLQ-C30 (p<0.01). Almost identical mean CARES-SF scores across groups (SCT: 0.7-1.4, ASCT: 0.8-1.3) were found at the subsequent assessments, consistent with the QLQ-C30 data. Correlations between CARES-SF and QLQ-C30 Physical Function Scales ranged from 0.45 to 0.65.

The SCT group had better psychosocial subscale scores (mean 0.4 and 0.5 versus ASCT: 0.7 and 0.8, p<0.01) at the 6 and 12-month assessments, as well as better satisfaction on the marital subscale (p=0.01) 6 months post-transplant.

Few patients requested specific help: 19% at baseline with 'fear of the cancer progressing' and 9% with 'reduction in physical energy' after 6 and 12 months.

Conclusion: The CARES-SF detected differences across groups of patients as well as within-patient changes over time. The possibility for patients to express their need for professional assistance renders the CARES-SF appropriate after SCT/ASCT. The sexual, marital and medical interaction subscales in particular address specific issues of relevance for follow-up care, compared with more traditional questionnaires assessing health related quality of life (HRQOL). Copyright (C) 2003 John Wiley Sons, Ltd.

Original languageEnglish
Pages (from-to)803-813
Number of pages10
JournalPsycho-Oncology
Volume12
DOIs
Publication statusPublished - 2003

Keywords

  • BONE-MARROW-TRANSPLANTATION
  • QUESTIONNAIRE
  • PREDICTORS
  • INSTRUMENT
  • POPULATION
  • SURVIVORS
  • THERAPY
  • QLQ-C30
  • LEVEL

Cite this

The CARES-SF used for prospective assessment of health related quality of life after stem cell transplantation. / Hjermstad, M. J.; Evensen, S. A.; kvaloy, S. O.; Loge, J. H.; Fayers, Peter; Kaasa, S.

In: Psycho-Oncology, Vol. 12, 2003, p. 803-813.

Research output: Contribution to journalArticle

Hjermstad, M. J. ; Evensen, S. A. ; kvaloy, S. O. ; Loge, J. H. ; Fayers, Peter ; Kaasa, S. / The CARES-SF used for prospective assessment of health related quality of life after stem cell transplantation. In: Psycho-Oncology. 2003 ; Vol. 12. pp. 803-813.
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T1 - The CARES-SF used for prospective assessment of health related quality of life after stem cell transplantation

AU - Hjermstad, M. J.

AU - Evensen, S. A.

AU - kvaloy, S. O.

AU - Loge, J. H.

AU - Fayers, Peter

AU - Kaasa, S.

PY - 2003

Y1 - 2003

N2 - Objective: By employing the Cancer Rehabilitation and Evaluation System short form (CARES-SF) prospectively we wanted to focus on the rehabilitation needs after high-dose chemotherapy (HDC) and stem cell transplantation, in order to identify problems that should be addressed by health-care professionals during the course of disease and treatment.Methods: The CARES-SF was administered before and at 2, 6 and 12 months post-transplant to 130 cancer patients treated with HDC and allogeneic (SCT) or autologous stem cell transplantation (ASCT). Physical function scale scores were compared with the corresponding scale of the EORTC QLQ-C30.Results: The SCT group reported significantly better physical function than the ASCT group before transplant on both the CARES-SF (p<0.0001) and the EORTC QLQ-C30 (p<0.01). Almost identical mean CARES-SF scores across groups (SCT: 0.7-1.4, ASCT: 0.8-1.3) were found at the subsequent assessments, consistent with the QLQ-C30 data. Correlations between CARES-SF and QLQ-C30 Physical Function Scales ranged from 0.45 to 0.65.The SCT group had better psychosocial subscale scores (mean 0.4 and 0.5 versus ASCT: 0.7 and 0.8, p<0.01) at the 6 and 12-month assessments, as well as better satisfaction on the marital subscale (p=0.01) 6 months post-transplant.Few patients requested specific help: 19% at baseline with 'fear of the cancer progressing' and 9% with 'reduction in physical energy' after 6 and 12 months.Conclusion: The CARES-SF detected differences across groups of patients as well as within-patient changes over time. The possibility for patients to express their need for professional assistance renders the CARES-SF appropriate after SCT/ASCT. The sexual, marital and medical interaction subscales in particular address specific issues of relevance for follow-up care, compared with more traditional questionnaires assessing health related quality of life (HRQOL). Copyright (C) 2003 John Wiley Sons, Ltd.

AB - Objective: By employing the Cancer Rehabilitation and Evaluation System short form (CARES-SF) prospectively we wanted to focus on the rehabilitation needs after high-dose chemotherapy (HDC) and stem cell transplantation, in order to identify problems that should be addressed by health-care professionals during the course of disease and treatment.Methods: The CARES-SF was administered before and at 2, 6 and 12 months post-transplant to 130 cancer patients treated with HDC and allogeneic (SCT) or autologous stem cell transplantation (ASCT). Physical function scale scores were compared with the corresponding scale of the EORTC QLQ-C30.Results: The SCT group reported significantly better physical function than the ASCT group before transplant on both the CARES-SF (p<0.0001) and the EORTC QLQ-C30 (p<0.01). Almost identical mean CARES-SF scores across groups (SCT: 0.7-1.4, ASCT: 0.8-1.3) were found at the subsequent assessments, consistent with the QLQ-C30 data. Correlations between CARES-SF and QLQ-C30 Physical Function Scales ranged from 0.45 to 0.65.The SCT group had better psychosocial subscale scores (mean 0.4 and 0.5 versus ASCT: 0.7 and 0.8, p<0.01) at the 6 and 12-month assessments, as well as better satisfaction on the marital subscale (p=0.01) 6 months post-transplant.Few patients requested specific help: 19% at baseline with 'fear of the cancer progressing' and 9% with 'reduction in physical energy' after 6 and 12 months.Conclusion: The CARES-SF detected differences across groups of patients as well as within-patient changes over time. The possibility for patients to express their need for professional assistance renders the CARES-SF appropriate after SCT/ASCT. The sexual, marital and medical interaction subscales in particular address specific issues of relevance for follow-up care, compared with more traditional questionnaires assessing health related quality of life (HRQOL). Copyright (C) 2003 John Wiley Sons, Ltd.

KW - BONE-MARROW-TRANSPLANTATION

KW - QUESTIONNAIRE

KW - PREDICTORS

KW - INSTRUMENT

KW - POPULATION

KW - SURVIVORS

KW - THERAPY

KW - QLQ-C30

KW - LEVEL

U2 - 10.1002/pon.708

DO - 10.1002/pon.708

M3 - Article

VL - 12

SP - 803

EP - 813

JO - Psycho-Oncology

JF - Psycho-Oncology

SN - 1057-9249

ER -