The control of histone gene expression

Alexander McRobb Rattray; Berndt Marino Muller

doi:10.1042/BST20120065

The control of histone gene expression

Alexander McRobb Rattray, Berndt Marino Muller

Medical Sciences

Research output: Contribution to journal › Literature review › peer-review

47 Citations (Scopus)

Abstract

Histone proteins are essential for the packaging of DNA into chromosomes. Histone gene expression is cell-cycle-regulated and coupled to DNA replication. Control of histone gene expression occurs at the transcriptional and post-transcriptional level and ensures that a fine balance between histone abundance and DNA replication is maintained for the correct packaging of newly replicated DNA into chromosomes. In the present paper, we review histone gene expression, highlighting the control mechanisms and key molecules involved in this process.

Original language	English
Pages (from-to)	880-885
Number of pages	6
Journal	Biochemical Society Transactions
Volume	40
Issue number	4
DOIs	https://doi.org/10.1042/BST20120065
Publication status	Published - Aug 2012

Keywords

cell cycle
DNA replication
histone gene expression
RNA degradation
RNA processing
translation

Access to Document

10.1042/BST20120065

http://www.biochemsoctrans.org/bst/040/0880/bst0400880.htm

Cite this

@article{0720d083df5d4620930d3ccb49336bf1,

title = "The control of histone gene expression",

abstract = "Histone proteins are essential for the packaging of DNA into chromosomes. Histone gene expression is cell-cycle-regulated and coupled to DNA replication. Control of histone gene expression occurs at the transcriptional and post-transcriptional level and ensures that a fine balance between histone abundance and DNA replication is maintained for the correct packaging of newly replicated DNA into chromosomes. In the present paper, we review histone gene expression, highlighting the control mechanisms and key molecules involved in this process.",

keywords = "cell cycle, DNA replication, histone gene expression, RNA degradation, RNA processing, translation",

author = "Rattray, {Alexander McRobb} and Muller, {Berndt Marino}",

year = "2012",

month = aug,

doi = "10.1042/BST20120065",

language = "English",

volume = "40",

pages = "880--885",

journal = "Biochemical Society Transactions",

issn = "0300-5127",

publisher = "Portland Press Ltd.",

number = "4",

}

TY - JOUR

T1 - The control of histone gene expression

AU - Rattray, Alexander McRobb

AU - Muller, Berndt Marino

PY - 2012/8

Y1 - 2012/8

N2 - Histone proteins are essential for the packaging of DNA into chromosomes. Histone gene expression is cell-cycle-regulated and coupled to DNA replication. Control of histone gene expression occurs at the transcriptional and post-transcriptional level and ensures that a fine balance between histone abundance and DNA replication is maintained for the correct packaging of newly replicated DNA into chromosomes. In the present paper, we review histone gene expression, highlighting the control mechanisms and key molecules involved in this process.

AB - Histone proteins are essential for the packaging of DNA into chromosomes. Histone gene expression is cell-cycle-regulated and coupled to DNA replication. Control of histone gene expression occurs at the transcriptional and post-transcriptional level and ensures that a fine balance between histone abundance and DNA replication is maintained for the correct packaging of newly replicated DNA into chromosomes. In the present paper, we review histone gene expression, highlighting the control mechanisms and key molecules involved in this process.

KW - cell cycle

KW - DNA replication

KW - histone gene expression

KW - RNA degradation

KW - RNA processing

KW - translation

U2 - 10.1042/BST20120065

DO - 10.1042/BST20120065

M3 - Literature review

SN - 0300-5127

VL - 40

SP - 880

EP - 885

JO - Biochemical Society Transactions

JF - Biochemical Society Transactions

IS - 4

ER -

The control of histone gene expression

Abstract

Keywords

Access to Document

Fingerprint

Cite this