The cost-effectiveness of a volunteer lifestyle coaching weight reduction programme for women attending routine breast cancer screening - results from the actwell trial

Background/purpose: There are several health impacts and large health care costs associated with overweight and obesity, including additional risk of developing type 2 diabetes, cardiovascular disease, breast and other cancers. These risks suggest a need to develop effective and cost-effective weight management programmes to reduce the prevalence of overweight and obesity. We report the costeffectiveness of a novel volunteer-led 12-month weight management programme (“ActWELL”) initiated in breast cancer screening centres across Scotland.
Methods: The cost-effectiveness of the ActWELL programme is measured relative to usual care, adopting the perspective of the National Health Service, using data from a four centre, 1:1 parallel group randomised controlled trial (n=560). We identify, measure and value health care resource use and health-related quality of life (using EQ-5D5L) data at baseline, three months and 12-month follow-up amongst women aged between 50-70 years of age with Body Mass Index
>25kg/m2 who attended routine breast cancer screening clinics and agreed to participate in the trial. The incremental cost per quality adjusted life year (QALY) gained over 12 months is calculated using the ratio of the difference in the mean costs and mean QALY across all participants. Primary analysis is conducted on an intention-to-treat basis and performed for participants with complete data on resource use and EQ-5D5L values. Additional analysis is also reported for missing data and the robustness of results tested using sensitivity analysis.
Results: Results will be available and presented.
Conclusions and Implications: The main conclusions and implications for policy and practice will be discussed.