The CXC chemokine receptors of fish: Insights into CXCR evolution in the vertebrates

Jun Zou, Anthony K Redmond, Zhitao Qi, Helen Marie Dooley, Christopher John Secombes

Research output: Contribution to journalArticle

26 Citations (Scopus)


This article will review current knowledge on CXCR in fish, that represent three distinct vertebrate groups: Agnatha (jawless fishes), Chondrichthyes (cartilaginous fishes) and Osteichthyes (bony fishes). With the sequencing of many fish genomes, information on CXCR in these species in particular has expanded considerably. In mammals, 6 CXCRs have been described, and their homologues will be initially reviewed before considering a number of atypical CXCRs and a discussion of CXCR evolution.

Original languageEnglish
Pages (from-to)117-131
Number of pages15
JournalGeneral and Comparative Endocrinology
Early online date23 Jan 2015
Publication statusPublished - 1 May 2015



  • CXC chemokine receptors
  • fish
  • vertebrates
  • evolution

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