The Demographic and Clinical Characteristics of Eosinophilic and non-Eosinophilic Phenotypes of Severe Asthma in International Severe Asthma Registry (ISAR)

Enrico Heffler; Trung N. Tran; Mona Al-Ahmad; Marianna Alacqua; Lakmini Bulathsinhala; John Busby; G. Walter Canonica; Victoria A. Carter; Isha Chaudhry; George C. Christoff; Borja G. Cosio; J. Mark FitzGerald; Liam G. Heaney; Takashi Iwanaga; David Jackson; Marjan Kerkhof; Chin Kook Rhee; Luis Perez-de-Llano; Andrew N. Menzies-Gow; Ruth B. Murray; Nikolaos G. Papadopoulos; Andriana L. Papaioannou; Paul Pfeffer; Todor A. Popov; Celeste Porsbjerg; Chris A. Price; Mohsen Sadatsafavi; Yuji Tohda; Eileen Wang; Michael E. Wechsler; James Zangrilli; David B. Price

The Demographic and Clinical Characteristics of Eosinophilic and non-Eosinophilic Phenotypes of Severe Asthma in International Severe Asthma Registry (ISAR)

Enrico Heffler, Trung N. Tran, Mona Al-Ahmad, Marianna Alacqua, Lakmini Bulathsinhala, John Busby, G. Walter Canonica, Victoria A. Carter, Isha Chaudhry, George C. Christoff, Borja G. Cosio, J. Mark FitzGerald, Liam G. Heaney, Takashi Iwanaga, David Jackson, Marjan Kerkhof, Chin Kook Rhee, Luis Perez-de-Llano, Andrew N. Menzies-Gow, Ruth B. MurrayNikolaos G. Papadopoulos, Andriana L. Papaioannou, Paul Pfeffer, Todor A. Popov, Celeste Porsbjerg, Chris A. Price, Mohsen Sadatsafavi, Yuji Tohda, Eileen Wang, Michael E. Wechsler, James Zangrilli, David B. Price

Research output: Contribution to conference › Abstract › peer-review

Abstract

Introduction: Severe asthma is a heterogenous disease with imprecise sub-classification into phenotypes based on clinical, functional or inflammatory parameters. Currently, there is a lack of information on overlapping and distinct characteristics of eosinophilic (EOS) and non-eosinophilic phenotypes in a global, real-life severe asthma cohort. This study aimed to describe and compare the baseline demographic and clinical characteristics between EOS and non-EOS phenotypes of severe asthma.

Original language	English
Publication status	Accepted/In press - 19 Mar 2020
Event	Respiratory Effectiveness Group Summit 2020 - Duration: 19 Mar 2020 → 21 Mar 2020

Conference

Conference	Respiratory Effectiveness Group Summit 2020
Period	19/03/20 → 21/03/20

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Heffler, E., Tran, T. N., Al-Ahmad, M., Alacqua, M., Bulathsinhala, L., Busby, J., Canonica, G. W., Carter, V. A., Chaudhry, I., Christoff, G. C., Cosio, B. G., FitzGerald, J. M., Heaney, L. G., Iwanaga, T., Jackson, D., Kerkhof, M., Rhee, C. K., Perez-de-Llano, L., Menzies-Gow, A. N., ... Price, D. B. (Accepted/In press). The Demographic and Clinical Characteristics of Eosinophilic and non-Eosinophilic Phenotypes of Severe Asthma in International Severe Asthma Registry (ISAR). Abstract from Respiratory Effectiveness Group Summit 2020.

Heffler, E, Tran, TN, Al-Ahmad, M, Alacqua, M, Bulathsinhala, L, Busby, J, Canonica, GW, Carter, VA, Chaudhry, I, Christoff, GC, Cosio, BG, FitzGerald, JM, Heaney, LG, Iwanaga, T, Jackson, D, Kerkhof, M, Rhee, CK, Perez-de-Llano, L, Menzies-Gow, AN, Murray, RB, Papadopoulos, NG, Papaioannou, AL, Pfeffer, P, Popov, TA, Porsbjerg, C, Price, CA, Sadatsafavi, M, Tohda, Y, Wang, E, Wechsler, ME, Zangrilli, J & Price, DB 2020, 'The Demographic and Clinical Characteristics of Eosinophilic and non-Eosinophilic Phenotypes of Severe Asthma in International Severe Asthma Registry (ISAR)', Respiratory Effectiveness Group Summit 2020, 19/03/20 - 21/03/20.

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title = "The Demographic and Clinical Characteristics of Eosinophilic and non-Eosinophilic Phenotypes of Severe Asthma in International Severe Asthma Registry (ISAR)",

abstract = "Introduction: Severe asthma is a heterogenous disease with imprecise sub-classification into phenotypes based on clinical, functional or inflammatory parameters. Currently, there is a lack of information on overlapping and distinct characteristics of eosinophilic (EOS) and non-eosinophilic phenotypes in a global, real-life severe asthma cohort. This study aimed to describe and compare the baseline demographic and clinical characteristics between EOS and non-EOS phenotypes of severe asthma.",

author = "Enrico Heffler and Tran, {Trung N.} and Mona Al-Ahmad and Marianna Alacqua and Lakmini Bulathsinhala and John Busby and Canonica, {G. Walter} and Carter, {Victoria A.} and Isha Chaudhry and Christoff, {George C.} and Cosio, {Borja G.} and FitzGerald, {J. Mark} and Heaney, {Liam G.} and Takashi Iwanaga and David Jackson and Marjan Kerkhof and Rhee, {Chin Kook} and Luis Perez-de-Llano and Menzies-Gow, {Andrew N.} and Murray, {Ruth B.} and Papadopoulos, {Nikolaos G.} and Papaioannou, {Andriana L.} and Paul Pfeffer and Popov, {Todor A.} and Celeste Porsbjerg and Price, {Chris A.} and Mohsen Sadatsafavi and Yuji Tohda and Eileen Wang and Wechsler, {Michael E.} and James Zangrilli and Price, {David B.}",

year = "2020",

month = mar,

day = "19",

language = "English",

note = "Respiratory Effectiveness Group Summit 2020 ; Conference date: 19-03-2020 Through 21-03-2020",

}

TY - CONF

T1 - The Demographic and Clinical Characteristics of Eosinophilic and non-Eosinophilic Phenotypes of Severe Asthma in International Severe Asthma Registry (ISAR)

AU - Heffler, Enrico

AU - Tran, Trung N.

AU - Al-Ahmad, Mona

AU - Alacqua, Marianna

AU - Bulathsinhala, Lakmini

AU - Busby, John

AU - Canonica, G. Walter

AU - Carter, Victoria A.

AU - Chaudhry, Isha

AU - Christoff, George C.

AU - Cosio, Borja G.

AU - FitzGerald, J. Mark

AU - Heaney, Liam G.

AU - Iwanaga, Takashi

AU - Jackson, David

AU - Kerkhof, Marjan

AU - Rhee, Chin Kook

AU - Perez-de-Llano, Luis

AU - Menzies-Gow, Andrew N.

AU - Murray, Ruth B.

AU - Papadopoulos, Nikolaos G.

AU - Papaioannou, Andriana L.

AU - Pfeffer, Paul

AU - Popov, Todor A.

AU - Porsbjerg, Celeste

AU - Price, Chris A.

AU - Sadatsafavi, Mohsen

AU - Tohda, Yuji

AU - Wang, Eileen

AU - Wechsler, Michael E.

AU - Zangrilli, James

AU - Price, David B.

PY - 2020/3/19

Y1 - 2020/3/19

N2 - Introduction: Severe asthma is a heterogenous disease with imprecise sub-classification into phenotypes based on clinical, functional or inflammatory parameters. Currently, there is a lack of information on overlapping and distinct characteristics of eosinophilic (EOS) and non-eosinophilic phenotypes in a global, real-life severe asthma cohort. This study aimed to describe and compare the baseline demographic and clinical characteristics between EOS and non-EOS phenotypes of severe asthma.

AB - Introduction: Severe asthma is a heterogenous disease with imprecise sub-classification into phenotypes based on clinical, functional or inflammatory parameters. Currently, there is a lack of information on overlapping and distinct characteristics of eosinophilic (EOS) and non-eosinophilic phenotypes in a global, real-life severe asthma cohort. This study aimed to describe and compare the baseline demographic and clinical characteristics between EOS and non-EOS phenotypes of severe asthma.

M3 - Abstract

T2 - Respiratory Effectiveness Group Summit 2020

Y2 - 19 March 2020 through 21 March 2020

ER -

The Demographic and Clinical Characteristics of Eosinophilic and non-Eosinophilic Phenotypes of Severe Asthma in International Severe Asthma Registry (ISAR)

Abstract

Conference

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