The Detection of Glycine from the Treatment of Glyoxylic acid with Iron(II) Sulfate and Ammonia in Water

Michael John Plater, Ken Vassiliev

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1 Citation (Scopus)
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Abstract

glycine/(NH4)2SO4 mixture was isolated by treatment of glyoxylic acid with FeSO4 and aqNH3 in H2O. The yields of glycine were estimated by 1H NMR. Pyruvic acid was not reduced to alanine under these conditions. This method for forming glycine might have occurred prebiotically alongside the Urey-Miller arc discharge method for making amino acids because glyoxylic acid is formed by arc discharge through a N2/CO2 atmosphere and both NH3 and Fe(II) occurred in the earth's early oceans. The carboxylic acid directs the reduction of 2,4-dinitrobenzoic acid to give 2-amino-4-nitrobenzoic acid.
Original languageEnglish
Pages (from-to)129-132
Number of pages4
JournalJournal of Chemical Research
Volume35
Issue number3
DOIs
Publication statusPublished - Mar 2011

Keywords

  • glyoxylic acid
  • iron(II)sulfate
  • ammonia
  • amino acid
  • ninhydrin
  • arc discharge

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