The Detection of Glycine from the Treatment of Glyoxylic acid with Iron(II) Sulfate and Ammonia in Water

Michael John Plater; Ken Vassiliev

doi:10.3184/174751911X12964930076809

The Detection of Glycine from the Treatment of Glyoxylic acid with Iron(II) Sulfate and Ammonia in Water

Michael John Plater, Ken Vassiliev

Chemistry

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2 Citations (Scopus)

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Abstract

glycine/(NH4)2SO4 mixture was isolated by treatment of glyoxylic acid with FeSO4 and aqNH3 in H2O. The yields of glycine were estimated by 1H NMR. Pyruvic acid was not reduced to alanine under these conditions. This method for forming glycine might have occurred prebiotically alongside the Urey-Miller arc discharge method for making amino acids because glyoxylic acid is formed by arc discharge through a N2/CO2 atmosphere and both NH3 and Fe(II) occurred in the earth's early oceans. The carboxylic acid directs the reduction of 2,4-dinitrobenzoic acid to give 2-amino-4-nitrobenzoic acid.

Original language	English
Pages (from-to)	129-132
Number of pages	4
Journal	Journal of Chemical Research
Volume	35
Issue number	3
DOIs	https://doi.org/10.3184/174751911X12964930076809
Publication status	Published - Mar 2011

Keywords

glyoxylic acid
iron(II)sulfate
ammonia
amino acid
ninhydrin
arc discharge

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10.3184/174751911X12964930076809

JCR The Detection of Glycine from the Treatment of Glyoxylic acid with Iron
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title = "The Detection of Glycine from the Treatment of Glyoxylic acid with Iron(II) Sulfate and Ammonia in Water",

abstract = " glycine/(NH4)2SO4 mixture was isolated by treatment of glyoxylic acid with FeSO4 and aqNH3 in H2O. The yields of glycine were estimated by 1H NMR. Pyruvic acid was not reduced to alanine under these conditions. This method for forming glycine might have occurred prebiotically alongside the Urey-Miller arc discharge method for making amino acids because glyoxylic acid is formed by arc discharge through a N2/CO2 atmosphere and both NH3 and Fe(II) occurred in the earth's early oceans. The carboxylic acid directs the reduction of 2,4-dinitrobenzoic acid to give 2-amino-4-nitrobenzoic acid. ",

keywords = "glyoxylic acid, iron(II)sulfate, ammonia, amino acid, ninhydrin, arc discharge",

author = "Plater, {Michael John} and Ken Vassiliev",

year = "2011",

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doi = "10.3184/174751911X12964930076809",

language = "English",

volume = "35",

pages = "129--132",

journal = "Journal of Chemical Research",

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T1 - The Detection of Glycine from the Treatment of Glyoxylic acid with Iron(II) Sulfate and Ammonia in Water

AU - Plater, Michael John

AU - Vassiliev, Ken

PY - 2011/3

Y1 - 2011/3

N2 - glycine/(NH4)2SO4 mixture was isolated by treatment of glyoxylic acid with FeSO4 and aqNH3 in H2O. The yields of glycine were estimated by 1H NMR. Pyruvic acid was not reduced to alanine under these conditions. This method for forming glycine might have occurred prebiotically alongside the Urey-Miller arc discharge method for making amino acids because glyoxylic acid is formed by arc discharge through a N2/CO2 atmosphere and both NH3 and Fe(II) occurred in the earth's early oceans. The carboxylic acid directs the reduction of 2,4-dinitrobenzoic acid to give 2-amino-4-nitrobenzoic acid.

AB - glycine/(NH4)2SO4 mixture was isolated by treatment of glyoxylic acid with FeSO4 and aqNH3 in H2O. The yields of glycine were estimated by 1H NMR. Pyruvic acid was not reduced to alanine under these conditions. This method for forming glycine might have occurred prebiotically alongside the Urey-Miller arc discharge method for making amino acids because glyoxylic acid is formed by arc discharge through a N2/CO2 atmosphere and both NH3 and Fe(II) occurred in the earth's early oceans. The carboxylic acid directs the reduction of 2,4-dinitrobenzoic acid to give 2-amino-4-nitrobenzoic acid.

KW - glyoxylic acid

KW - iron(II)sulfate

KW - ammonia

KW - amino acid

KW - ninhydrin

KW - arc discharge

U2 - 10.3184/174751911X12964930076809

DO - 10.3184/174751911X12964930076809

M3 - Article

VL - 35

SP - 129

EP - 132

JO - Journal of Chemical Research

JF - Journal of Chemical Research

SN - 0308-2342

IS - 3

ER -

The Detection of Glycine from the Treatment of Glyoxylic acid with Iron(II) Sulfate and Ammonia in Water

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